Antibiotic-mediated perturbation of the gut microbiome is associated with numerous
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …

Rational use of antibiotic is the key approach to improve the antibiotic performance and
tackling of the antimicrobial resistance. The efficacy of antimicrobials are influenced by many …

Antibiotics are deployed against bacterial pathogens, but their targeting of conserved
microbial processes means they also collaterally perturb the commensal microbiome. To …

Hospitalized preterm infants receive frequent and often prolonged exposures to antibiotics
because they are vulnerable to infection. It is not known whether the short-term effects of …

As global biodiversity continues to reduce at an alarming rate, threatened species are
increasingly being brought under intensive management or into captivity. However, current …

Early development of the microbiome has been shown to affect general health and physical
development of the infant and, although some studies have been undertaken in high-income …

The biosynthesis of antibiotics and self-protection mechanisms employed by antibiotic
producers are an integral part of the growing antibiotic resistance threat. The origins of …

Necrotizing enterocolitis (NEC) is a serious consequence of preterm birth and is often
associated with gut bacterial microbiome alterations. However, little is known about the …

Background Inappropriate antimicrobial usage is a key driver of antimicrobial resistance
(AMR). Low-and middle-income countries (LMICs) are disproportionately burdened by AMR …

Resistance to antibiotics is becoming a worldwide threat as infections caused by multidrug-
resistant pathogenic microorganisms can overcome antibiotic treatments and spread quickly …