Background Prolongation of the corrected QT (QTc) interval is a key issue for patients who
receive psychotropic medications. Such patients may have baseline clinical risk factors for …

Method We searched PubMed for pertinent literature on the risk of QTc prolongation and/or
TdP associated with commonly used psychotropic drugs. Results Thioridazine and …

We comprehensively reviewed published literature to determine whether it supported the
link between corrected QT (QTc) interval prolongation and torsade de pointes (TdP) for the …

Choosing an appropriate treatment for chronic pain remains problematic, and despite the
available medication for its treatment, still, many patients complain about pain and appeal to …

There is a definite correlation between cardiovascular diseases and depressive disorders.
Nevertheless, many aspects of this association have yet to be fully elucidated. Up to half of …

What is already known about this subject• Recent concerns about lack of cardiovascular
safety have led to restrictions in the use of venlafaxine in the UK.• Venlafaxine may …

Depressed patients are at increased risk of cardiovascular (CV) disease (CVD) and those
with concomitant depression and CVD are at increased risk of death. The safety and efficacy …

The quinidine-like effects of some antidepressant drugs (particularly tricyclic
antidepressants) and many antipsychotic drugs (particularly the phenothiazines) confound …

Objective: To review QT prolongation potential with newer nonselective serotonin reuptake
inhibitor (non-SSRI) antidepressants. Data Sources: A PubMed literature search was …

Abstract Background: Antidepressants (ADs) are known to have the potential to cause
various cardiovascular adverse drug reactions (ADRs). The tricyclic antidepressants (TCAs) …