Signal transducer and activator of transcription 3 (STAT3), a member of the STAT family,
discovered in the cytoplasm of almost all types of mammalian cells, plays a significant role in …

Proteins of the signal transducer and activator of transcription (STAT) family mediate cellular
responses to cytokines and growth factors. Aberrant regulation of the STAT3 oncogene …

Head and neck cancer is one of the most prevalent cancers around the world. Head and
neck squamous cell carcinoma (HNSCC) accounts for nearly 90% of head and neck cancer …

Human papillomaviruses (HPVs), which are small, double-stranded, circular DNA viruses
infecting human epithelial cells, are associated with various benign and malignant lesions of …

Human papillomavirus (HPV) is a class of envelope-free double-stranded DNA virus. HPV
infection has been strongly associated with the development of many malignancies, such as …

Head and neck squamous cell carcinomas (HNSCCs) are the eighth most common cancers
worldwide. While promising new therapies are emerging, cisplatin-based chemotherapy …

Nasopharyngeal carcinoma (NPC) is characterized by a high rate of local invasion and early
distant metastasis. Increasing evidence indicates that epigenetic abnormalities play …

Laryngopharyngeal reflux, a variant of gastroesophageal reflux disease, has been
considered a risk factor in the development of hypopharyngeal cancer. Bile acids are …

Human papillomaviruses (HPVs) are small, DNA viruses that cause around 5% of all
cancers in humans, including almost all cervical cancer cases and a significant proportion of …

Microbiome studies show altered microbiota in head and neck squamous cell carcinoma
(HNSCC), both in terms of taxonomic composition and metabolic capacity. These studies …