The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Obesity is one of the most prevalent health conditions in humans and companion animals
globally. It is associated with premature mortality, metabolic dysfunction, and multiple health …

Abstract Background The international Dog10K project aims to sequence and analyze
several thousand canine genomes. Incorporating 20× data from 1987 individuals, including …

DNA methylation profiles have been used to develop biomarkers of aging known as
epigenetic clocks, which predict chronological age with remarkable accuracy and show …

Selective breeding of domestic dogs has generated diverse breeds often optimized for
performing specialized tasks. Despite the heritability of breed-typical behavioral traits …

Dogs are uniquely associated with human dispersal and bring transformational insight into
the domestication process. Dingoes represent an intriguing case within canine evolution …

Abstract We present GSD_1. 0, a high-quality domestic dog reference genome with
chromosome length scaffolds and contiguity increased 55-fold over CanFam3. 1. Annotation …

Gene retrocopies arise from the reverse transcription and insertion into the genome of
processed mRNA transcripts. Although many retrocopies have acquired mutations that …

Recent advances in long-read sequencing have enabled the creation of reference-quality
genome assemblies for multiple individuals within a species. In particular, 8 long-read …

The domestic dog has evolved to be an important biomedical model for studies regarding
the genetic basis of disease, morphology and behavior. Genetic studies in the dog have …