Antifibrinolytic drugs for treating primary postpartum haemorrhage

H Shakur, D Beaumont, S Pavord… - Cochrane Database …, 1996 - cochranelibrary.com
Background Postpartum haemorrhage (PPH)‐heaving bleeding within the first 24 hours after
giving birth‐is one of the main causes of death of women after childbirth. Antifibrinolytics …

[HTML][HTML] Tranexamic acid for post-partum haemorrhage: What, who and when

A Brenner, K Ker, H Shakur-Still, I Roberts - Best Practice & Research …, 2019 - Elsevier
Tranexamic acid reduces bleeding by inhibiting the breakdown of blood clots. It is cost-
effective and heat-stable with a long shelf life. In the WOMAN trial, tranexamic acid reduced …

The WOMAN trial: clinical and contextual factors surrounding the deaths of 483 women following post-partum haemorrhage in developing countries

R Picetti, L Miller, H Shakur-Still, T Pepple… - BMC Pregnancy and …, 2020 - Springer
Background Post-partum haemorrhage (PPH) is a leading cause of maternal death
worldwide. The WOMAN trial assessed the effects of tranexamic acid (TXA) on death and …

[HTML][HTML] Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): a single-centre, randomised, double-blind …

H Shakur-Still, I Roberts, B Fawole, M Kuti… - Wellcome open …, 2018 - ncbi.nlm.nih.gov
Background: Postpartum haemorrhage (PPH) is a leading cause of maternal death. The
WOMAN trial showed that tranexamic acid (TXA) reduces death due to bleeding in women …

Prophylactic use of tranexamic acid reduces blood loss and transfusion requirements in patients undergoing cesarean section: A meta‐analysis

Y Wang, S Liu, L He - Journal of Obstetrics and Gynaecology …, 2019 - Wiley Online Library
Aim Tranexamic acid (TXA) has been used to treat peripartum hemorrhage, while
preoperative use of TXA in cesarean section (CS) remains controversial. To assess the …

Viscoelastic haemostatic point‐of‐care assays in the management of postpartum haemorrhage: a narrative review

JD Dias, AJ Butwick, J Hartmann, JH Waters - Anaesthesia, 2022 - Wiley Online Library
Viscoelastic haemostatic assays provide rapid testing at the bed‐side that identify all phases
of haemostasis, from initial fibrin formation to clot lysis. In obstetric patients, altered …

Influence of the WOMAN trial on national wide standard operating procedures for treatment of postpartum hemorrhage

FJ Raimann, L Jennewein, M Sonntagbauer… - Journal of Gynecology …, 2019 - Elsevier
Background Postpartum hemorrhage is the leading cause of maternal death. Recently, the
WOMAN trial showed that early administration of tranexamic acid leads to a reduced …

Utilidad del ácido tranexámico vía oral para la prevención de la hemorragia obstétrica en mujeres con embarazo de término

ACB Sánchez, OC López - Archivos de Investigación Materno …, 2023 - medigraphic.com
Introducción: la hemorragia obstétrica es una de las principales causas de muerte materna
en el mundo. Reconocidos grupos de estudio a nivel mundial han recomendado identificar …

Usefulness of oral tranexamic acid for the prevention of obstetric haemorrhage in women with term pregnancy

ACB Sánchez, OC López - Archivos de Investigación Materno …, 2023 - medigraphic.com
Introduction: obstetric hemorrhage is one of the main causes of maternal death in the world.
The main study groups worldwide have recommended early identification of risk factors and …

Development of Three-Dimensional Neuronal Model Systems for Mechanical Stress Application

عارضة, محمود - 2021‎ - repository.najah.edu
Figure 1.5: The figure represents a comparison between 2D and 3D cell culture. A
represents a 2D culture that is coated with protein, and B is a 3D culture on a scaffold. As …