[HTML][HTML] Recent advances in magnetic resonance neurospectroscopy

Y Rosen, RE Lenkinski - Neurotherapeutics, 2007 - Elsevier
Over the past two decades, proton magnetic resonance spectroscopy (proton MRS) of the
brain has made the transition from research tool to a clinically useful modality. In this review …

Clinical applications of proton MR spectroscopy in oncology

L Kwock, JK Smith, M Castillo… - … in cancer research …, 2002 - journals.sagepub.com
Proton magnetic resonance spectroscopy (H1-MRS) has been increasingly receiving more
attention from radiologists, neurosurgeons, radiation and medical oncologists in the “in situ” …

Measurement of brain glutamate using TE‐averaged PRESS at 3T

R Hurd, N Sailasuta, R Srinivasan… - … in Medicine: An …, 2004 - Wiley Online Library
A method is introduced that provides improved in vivo spectroscopic measurements of
glutamate (Glu), glutamine (Gln), choline (Cho), creatine (Cre), N‐acetyl compounds (NAtot …

Localized two‐dimensional shift correlated MR spectroscopy of human brain

MA Thomas, K Yue, N Binesh… - … in Medicine: An …, 2001 - Wiley Online Library
Abstract A two‐dimensional (2D) chemical shift correlated MR spectroscopic (COSY)
sequence integrated into a new volume localization technique (90°–180°–90°) is proposed …

Impaired brain GABA in focal dystonia

LM Levy, M Hallett - Annals of Neurology: Official Journal of the …, 2002 - Wiley Online Library
Patients with task‐specific dystonia (writer's cramp) have impaired cortical inhibition likely
arising from striatal dysfunction. However, the levels of the inhibitory neurotransmitter …

Rapid modulation of GABA in sensorimotor cortex induced by acute deafferentation

LM Levy, U Ziemann, R Chen… - Annals of Neurology …, 2002 - Wiley Online Library
Recovery of function after acute injury to the central nervous system may be controlled by
the availability of γ‐aminobutyric acid (GABA), the main inhibitory neurotransmitter in the …

Proton MR spectroscopy of prostatic tissue focused on the etection of spermine, a possible biomarker of malignant behavior in prostate cancer

M van der Graaf, RG Schipper, GON Oosterhof… - … Resonance Materials in …, 2000 - Springer
To investigate whether polyamines may be valuable diagnostic and prognostic markers in
prostate cancer, the presence of alyamines was studied in various human prostatic tissues …

Noninvasive magnetic resonance spectroscopic imaging biomarkers to predict the clinical grade of pediatric brain tumors

LG Astrakas, D Zurakowski, AA Tzika, MK Zarifi… - Clinical cancer …, 2004 - AACR
The diagnosis and therapy of childhood brain tumors, most of which are low grade, can be
complicated because of their frequent adjacent location to crucial structures, which limits …

Two-dimensional linear-combination model fitting of magnetic resonance spectra to define the macromolecule baseline using FiTAID, a Fitting Tool for Arrays of …

DGQ Chong, R Kreis, CS Bolliger, C Boesch… - … resonance materials in …, 2011 - Springer
Object To propose the determination of the macromolecular baseline (MMBL) in clinical 1H
MR spectra based on T 1 and T 2 differentiation using 2D fitting in FiTAID, a general Fitting …

Improved two‐dimensional J‐resolved spectroscopy

RF Schulte, T Lange, J Beck, D Meier… - NMR in Biomedicine …, 2006 - Wiley Online Library
Localised two‐dimensional J‐resolved spectroscopy (JPRESS) is optimised for the in vivo
detection of J‐coupled metabolites using magnetic resonance spectroscopy at 3 T. The …