Heavy metals and human health: Possible exposure pathways and the competition for protein binding sites

D Witkowska, J Słowik, K Chilicka - Molecules, 2021 - mdpi.com
Heavy metals enter the human body through the gastrointestinal tract, skin, or via inhalation.
Toxic metals have proven to be a major threat to human health, mostly because of their …

Sulfhydryl groups as targets of mercury toxicity

OP Ajsuvakova, AA Tinkov, M Aschner… - Coordination chemistry …, 2020 - Elsevier
The present study addresses existing data on the affinity and conjugation of sulfhydryl (thiol;-
SH) groups of low-and high-molecular-weight biological ligands with mercury (Hg). The …

Arsenic, lead, mercury and cadmium: Toxicity, levels in breast milk and the risks for breastfed infants

FM Rebelo, ED Caldas - Environmental research, 2016 - Elsevier
Metals are ubiquitous in nature, being found in all environmental compartments, and have a
variety of applications in human activities. Metals are transferred by maternal blood to the …

Biomarkers of mercury toxicity: Past, present, and future trends

V Branco, S Caito, M Farina… - Journal of Toxicology …, 2017 - Taylor & Francis
Mercury (Hg) toxicity continues to represent a global health concern. Given that human
populations are mostly exposed to low chronic levels of mercurial compounds …

Recent advances in the determination of elemental impurities in pharmaceuticals–Status, challenges and moving frontiers

V Balaram - Trac trends in Analytical chemistry, 2016 - Elsevier
Elemental impurities have been regulated in pharmaceutical products for many decades.
Metal impurities such as As, Cd, Cu, Pb, Hg, V and Pt in pharmaceuticals and drugs are …

Multifaceted functions of RPS27a: An unconventional ribosomal protein

J Luo, H Zhao, L Chen, M Liu - Journal of Cellular Physiology, 2023 - Wiley Online Library
The ribosomal protein S27a (RPS27a) is cleaved from the fusion protein ubiquitin–RPS27a
(Ub–RPS27a). Generally, Ub and RPS27a are coexpressed as a fusion protein but function …

Mercury in aquatic fauna contamination: a systematic review on its dynamics and potential health risks

P de Almeida Rodrigues, RG Ferrari… - Journal of …, 2019 - Elsevier
Mercury is an important pollutant, released into aquatic ecosystems both naturally and by
anthropogenic action. This element is transferred to aquatic organisms in different ways …

Epigallocatechin gallate for management of heavy metal-induced oxidative stress: Mechanisms of action, efficacy, and concerns

I Zwolak - International Journal of Molecular Sciences, 2021 - mdpi.com
In this review, we highlight the effects of epigallocatechin gallate (EGCG) against toxicities
induced by heavy metals (HMs). This most active green tea polyphenol was demonstrated to …

Toxicity of organic and inorganic mercury species in differentiated human neurons and human astrocytes

H Lohren, L Blagojevic, R Fitkau, F Ebert… - Journal of Trace …, 2015 - Elsevier
Organic mercury (Hg) species exert their toxicity primarily in the central nervous system. The
food relevant Hg species methylmercury (MeHg) has been frequently studied regarding its …

The myth of vaccination and autism spectrum

LV Gabis, OL Attia, M Goldman, N Barak… - European Journal of …, 2022 - Elsevier
Background Among all of the studied potential causes of autism, vaccines have received
some of the most scrutiny and have been the topic of many evidence-based studies. These …