The gut microbiome and inflammatory bowel diseases
Y Shan, M Lee, EB Chang - Annual review of medicine, 2022 - annualreviews.org
Inflammatory bowel diseases (IBD) arise from a convergence of genetic risk, environmental
factors, and gut microbiota, where each is necessary but not sufficient to cause disease …
factors, and gut microbiota, where each is necessary but not sufficient to cause disease …
Diversity and dynamism of IgA− microbiota interactions
IgA mediates microbial homeostasis at the intestinal mucosa. Within the gut, IgA acts in a
context-dependent manner to both prevent and promote bacterial colonization and to …
context-dependent manner to both prevent and promote bacterial colonization and to …
Reductions in anti-inflammatory gut bacteria are associated with depression in a sample of young adults
We assessed the gut microbiota of 90 American young adults, comparing 43 participants
with major depressive disorder (MDD) and 47 healthy controls, and found that the MDD …
with major depressive disorder (MDD) and 47 healthy controls, and found that the MDD …
[HTML][HTML] Interaction between commensal bacteria, immune response and the intestinal barrier in inflammatory bowel disease
Y Chen, W Cui, X Li, H Yang - Frontiers in Immunology, 2021 - frontiersin.org
In inflammatory bowel disease (IBD), intestinal mucosa cell and intestinal epithelial cell are
severely damaged, and then their susceptibility to bacteria increases, so many commensal …
severely damaged, and then their susceptibility to bacteria increases, so many commensal …
The CD4+ T cell response to a commensal-derived epitope transitions from a tolerant to an inflammatory state in Crohn's disease
Reciprocal interactions between host T helper cells and gut microbiota enforce local
immunological tolerance and modulate extra-intestinal immunity. However, our …
immunological tolerance and modulate extra-intestinal immunity. However, our …
Biological chemotaxis-guided self-thermophoretic nanoplatform augments colorectal cancer therapy through autonomous mucus penetration
ZH Wang, M Chu, N Yin, W Huang, W Liu, Z Zhang… - Science …, 2022 - science.org
Oral drug delivery systems have great potential to treat colorectal cancer (CRC). However,
the drug delivery efficiency is restricted by limited CRC-related intestine positioning and …
the drug delivery efficiency is restricted by limited CRC-related intestine positioning and …
Not all fibers are born equal; variable response to dietary fiber subtypes in IBD
H Armstrong, I Mander, Z Zhang, D Armstrong… - Frontiers in …, 2021 - frontiersin.org
Diet provides a safe and attractive alternative to available treatment options in a variety of
diseases; however, research has only just begun to elucidate the role of diet in chronic …
diseases; however, research has only just begun to elucidate the role of diet in chronic …
Label or concept–what is a pathobiont?
L Jochum, B Stecher - Trends in microbiology, 2020 - cell.com
An increasing number of microorganisms are classified as' pathobionts'(ie, organisms that
can cause harm under certain circumstances) but there exist no universally used criteria for …
can cause harm under certain circumstances) but there exist no universally used criteria for …
Lychee (Litchi chinensis Sonn.) Pulp Phenolics Activate the Short-Chain Fatty Acid-Free Fatty Acid Receptor Anti-inflammatory Pathway by Regulating Microbiota and …
G Huang, Z Wang, G Wu, R Zhang… - Journal of Agricultural …, 2021 - ACS Publications
The preventive effect of lychee pulp phenolics (LPP) on dextran sulfate sodium (DSS)-
induced colitis of mice and its underlying mechanisms were investigated in this research …
induced colitis of mice and its underlying mechanisms were investigated in this research …
[HTML][HTML] Pathobionts in inflammatory bowel disease: origins, underlying mechanisms, and implications for clinical care
The gut microbiota plays a significant role in the pathogenesis of both forms of inflammatory
bowel disease (IBD), namely Crohn's disease (CD) and ulcerative colitis (UC). While …
bowel disease (IBD), namely Crohn's disease (CD) and ulcerative colitis (UC). While …