[HTML][HTML] Plasmin and plasminogen system in the tumor microenvironment: implications for cancer diagnosis, prognosis, and therapy

AG Bharadwaj, RW Holloway, VA Miller, DM Waisman - Cancers, 2021 - mdpi.com
Simple Summary In this review, we present a detailed discussion of how the plasminogen-
activation system is utilized by tumor cells in their unrelenting attack on the tissues …

[HTML][HTML] Annexin A2 and cancer: A systematic review

MV Christensen, CK Høgdall… - International …, 2018 - spandidos-publications.com
Annexin A2 is a 36-kDa protein interfering with multiple cellular processes especially in
cancer progression. The present review aimed to show the relations between Annexin A2 …

Annexin A2: The diversity of pathological effects in tumorigenesis and immune response

Y Huang, M Jia, X Yang, H Han, G Hou… - … Journal of Cancer, 2022 - Wiley Online Library
Abstract Annexin A2 (ANXA2) is widely used as a marker in a variety of tumors. By
regulating multiple signal pathways, ANXA2 promotes the epithelial‐mesenchymal …

[HTML][HTML] Annexin animal models—from fundamental principles to translational research

T Grewal, C Rentero, C Enrich, M Wahba… - International Journal of …, 2021 - mdpi.com
Routine manipulation of the mouse genome has become a landmark in biomedical
research. Traits that are only associated with advanced developmental stages can now be …

[HTML][HTML] S100A10 accelerates aerobic glycolysis and malignant growth by activating mTOR-signaling pathway in gastric cancer

Y Li, XY Li, LX Li, RC Zhou, Y Sikong, X Gu… - Frontiers in cell and …, 2020 - frontiersin.org
S100 calcium-binding protein A10 (S100A10) is crucially involved in the tumorigenesis of
multiple malignant tumors. Reprogrammed glucose metabolism is emerging as a hallmark of …

[HTML][HTML] Modulation of ion channels and receptors by p11 (S100A10)

JS Seo, P Svenningsson - Trends in pharmacological sciences, 2020 - cell.com
p11 (S100A10, annexin II light chain, calpactin I light chain) is a multifunctional protein that
forms a heterotetrameric complex with Annexin A2, particularly at cell membranes. p11 …

[HTML][HTML] The bone marrow microenvironment in B-cell development and malignancy

AM Hughes, V Kuek, RS Kotecha, LC Cheung - Cancers, 2022 - mdpi.com
Simple Summary B cells are an essential component of the immune system and develop in
the bone marrow microenvironment. B-cell development is tightly regulated by the stromal …

Multiple functions of S100A10, an important cancer promoter

Y Saiki, A Horii - Pathology international, 2019 - Wiley Online Library
The S100 group of calcium binding proteins is composed of 21 members that exhibit
tissue/cell specific expressions. These S100 proteins bind a diverse range of targets and …

[HTML][HTML] Açaí (Euterpe oleracea Mart.) Seed Oil Exerts a Cytotoxic Role over Colorectal Cancer Cells: Insights of Annexin A2 Regulation and Molecular Modeling

MACN Da Silva, JW Tessmann, KRA Borges, LAS Wolff… - Metabolites, 2023 - mdpi.com
Açaí, Euterpe oleracea Mart., is a native plant from the Amazonian and is rich in several
phytochemicals with anti-tumor activities. The aim was to analyze the effects of açaí seed oil …

[HTML][HTML] S100A10 and cancer hallmarks: structure, functions, and its emerging role in ovarian cancer

TM Noye, NA Lokman, MK Oehler… - International journal of …, 2018 - mdpi.com
S100A10, which is also known as p11, is located in the plasma membrane and forms a
heterotetramer with annexin A2. The heterotetramer, comprising of two subunits of annexin …