Molecular mechanisms of atopic dermatitis pathogenesis
J Sroka-Tomaszewska, M Trzeciak - International journal of molecular …, 2021 - mdpi.com
Atopic dermatitis is a chronic, non-infectious inflammatory dermatosis. Acharacteristic
feature is persistent itching of the skin. The chronic, relapsing course of the disease …
feature is persistent itching of the skin. The chronic, relapsing course of the disease …
Early life microbial exposures and allergy risks: opportunities for prevention
H Renz, C Skevaki - Nature Reviews Immunology, 2021 - nature.com
Allergies, including asthma, food allergy and atopic dermatitis, are increasing in prevalence,
particularly in westernized countries. Although a detailed mechanistic explanation for this …
particularly in westernized countries. Although a detailed mechanistic explanation for this …
Delayed gut microbiota maturation in the first year of life is a hallmark of pediatric allergic disease
C Hoskinson, DLY Dai, KL Del Bel, AB Becker… - Nature …, 2023 - nature.com
Allergic diseases affect millions of people worldwide. An increase in their prevalence has
been associated with alterations in the gut microbiome, ie, the microorganisms and their …
been associated with alterations in the gut microbiome, ie, the microorganisms and their …
Allergen immunotherapy in children user's guide
Allergen immunotherapy is a cornerstone in the treatment of allergic children. The clinical
efficiency relies on a well‐defined immunologic mechanism promoting regulatory T cells and …
efficiency relies on a well‐defined immunologic mechanism promoting regulatory T cells and …
Research progress in atopic march
L Yang, J Fu, Y Zhou - Frontiers in immunology, 2020 - frontiersin.org
The incidence of allergic diseases continues to rise. Cross-sectional and longitudinal
studies have indicated that allergic diseases occur in a time-based order: from atopic …
studies have indicated that allergic diseases occur in a time-based order: from atopic …
The promise of the gut microbiome as part of individualized treatment strategies
DA Schupack, RAT Mars, DH Voelker… - Nature reviews …, 2022 - nature.com
Variability in disease presentation, progression and treatment response has been a central
challenge in medicine. Although variability in host factors and genetics are important, it has …
challenge in medicine. Although variability in host factors and genetics are important, it has …
Daily emollient during infancy for prevention of eczema: the BEEP randomised controlled trial
JR Chalmers, RH Haines, LE Bradshaw… - The Lancet, 2020 - thelancet.com
Background Skin barrier dysfunction precedes eczema development. We tested whether
daily use of emollient in the first year could prevent eczema in high-risk children. Methods …
daily use of emollient in the first year could prevent eczema in high-risk children. Methods …
Epicutaneous sensitization in the development of food allergy: what is the evidence and how can this be prevented?
There is increasing evidence regarding the importance of allergic sensitization through the
skin. In this review, we provide an overview of the atopic march and immune mechanism …
skin. In this review, we provide an overview of the atopic march and immune mechanism …
[HTML][HTML] The burden of asthma, hay fever and eczema in adults in 17 countries: GAN Phase I study
Aims Asthma, hay fever and eczema are three common chronic conditions. There have been
no recent multi-country data on the burden of these three conditions in adults; the aims of …
no recent multi-country data on the burden of these three conditions in adults; the aims of …
Epithelial barrier repair and prevention of allergy
E Goleva, E Berdyshev… - The Journal of clinical …, 2019 - Am Soc Clin Investig
Allergic diseases have in common a dysfunctional epithelial barrier, which allows the
penetration of allergens and microbes, leading to the release of type 2 cytokines that drive …
penetration of allergens and microbes, leading to the release of type 2 cytokines that drive …