Fluorescent proteins and genetically encoded biosensors

M Wang, Y Da, Y Tian - Chemical Society Reviews, 2023 - pubs.rsc.org
The genetically encoded fluorescent sensors convert chemical and physical signals into
light. They are powerful tools for the visualisation of physiological processes in living cells …

Genetically encoded biosensors for microbial synthetic biology: from conceptual frameworks to practical applications

W Yu, X Xu, K Jin, Y Liu, J Li, G Du, X Lv, L Liu - Biotechnology Advances, 2023 - Elsevier
Genetically encoded biosensors are the vital components of synthetic biology and metabolic
engineering, as they are regarded as powerful devices for the dynamic control of genotype …

[HTML][HTML] The European Polysaccharide Network of Excellence (EPNOE) research roadmap 2040: Advanced strategies for exploiting the vast potential of …

M Gericke, AJR Amaral, T Budtova, P De Wever… - Carbohydrate …, 2024 - Elsevier
Polysaccharides are among the most abundant bioresources on earth and consequently
need to play a pivotal role when addressing existential scientific challenges like climate …

Biosensor-guided discovery and engineering of metabolic enzymes

HG Hwang, DY Ye, GY Jung - Biotechnology Advances, 2023 - Elsevier
A variety of chemicals have been produced through metabolic engineering approaches, and
enhancing biosynthesis performance can be achieved by using enzymes with high catalytic …

Toward a modeling, optimization, and predictive control framework for fed‐batch metabolic cybergenetics

S Espinel‐Ríos, B Morabito, J Pohlodek… - Biotechnology and …, 2024 - Wiley Online Library
Biotechnology offers many opportunities for the sustainable manufacturing of valuable
products. The toolbox to optimize bioprocesses includes extracellular process elements …

Progress in pH-Sensitive sensors: essential tools for organelle pH detection, spotlighting mitochondrion and diverse applications

SA Li, XY Meng, YJ Zhang, CL Chen, YX Jiao… - Frontiers in …, 2024 - frontiersin.org
pH-sensitive fluorescent proteins have revolutionized the field of cellular imaging and
physiology, offering insight into the dynamic pH changes that underlie fundamental cellular …

Genetically encoded fluorescent biosensors for GPCR research

H Kim, IY Baek, J Seong - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
G protein-coupled receptors (GPCRs) regulate a wide range of physiological and
pathophysiological cellular processes, thus it is important to understand how GPCRs are …

Emerging biophysical techniques for probing synaptic transmission in neurodegenerative disorders

MB Kale, NL Wankhede, AK Bishoyi, S Ballal, R Kalia… - Neuroscience, 2024 - Elsevier
Plethora of research has shed light on the critical role of synaptic dysfunction in various
neurodegenerative disorders (NDDs), including Alzheimer's disease (AD), Parkinson's …

Genetically Encoded Fluorogenic DNA Aptamers for Imaging Metabolite in Living Cells

Y Wu, W Kong, J Van Stappen, L Kong… - Journal of the …, 2024 - ACS Publications
Genetically encoded fluorescent protein and fluorogenic RNA sensors are indispensable
tools for imaging biomolecules in cells. To expand the toolboxes and improve the …

Immobilization of recombinant fluorescent biosensors permits imaging of extracellular ion signals

S Burgstaller, H Bischof, T Rauter, T Schmidt… - Acs …, 2021 - ACS Publications
Given the importance of ion gradients and fluxes in biology, monitoring ions locally at the
exterior of the plasma membrane of intact cells in a noninvasive manner is highly desirable …