Chemical glycoproteomics

KK Palaniappan, CR Bertozzi - Chemical reviews, 2016 - ACS Publications
Chemical tools have accelerated progress in glycoscience, reducing experimental barriers
to studying protein glycosylation, the most widespread and complex form of posttranslational …

Matrix‐assisted laser desorption/ionization mass spectrometry of carbohydrates

DJ Harvey - Mass spectrometry reviews, 1999 - Wiley Online Library
This review describes the application of matrix‐assisted laser desorption/ionization (MALDI)
mass spectrometry to carbohydrate analysis and covers the period 1991–1998. The …

Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry

H Zhang, X Li, DB Martin, R Aebersold - Nature biotechnology, 2003 - nature.com
Quantitative proteome profiling using stable isotope protein tagging and automated tandem
mass spectrometry (MS/MS) is an emerging technology with great potential for the functional …

Lectin affinity capture, isotope-coded tagging and mass spectrometry to identify N-linked glycoproteins

H Kaji, H Saito, Y Yamauchi, T Shinkawa… - Nature …, 2003 - nature.com
We describe here a strategy for the large-scale identification of N-glycosylated proteins from
a complex biological sample. The approach, termed isotope-coded glycosylation-site …

Anti-NMDA receptor encephalitis antibody binding is dependent on amino acid identity of a small region within the GluN1 amino terminal domain

AJ Gleichman, LA Spruce, J Dalmau… - Journal of …, 2012 - Soc Neuroscience
Anti-NMDA receptor (NMDAR) encephalitis is a newly identified autoimmune disorder that
targets NMDARs, causing severe neurological symptoms including hallucinations …

A new strategy for identification of N-glycosylated proteins and unambiguous assignment of their glycosylation sites using HILIC enrichment and partial …

P Hägglund, J Bunkenborg, F Elortza… - Journal of proteome …, 2004 - ACS Publications
Characterization of glycoproteins using mass spectrometry ranges from determination of
carbohydrate-protein linkages to the full characterization of all glycan structures attached to …

Glycopeptide enrichment and separation for protein glycosylation analysis

S Ongay, A Boichenko, N Govorukhina… - Journal of separation …, 2012 - Wiley Online Library
Protein glycosylation plays key roles in many biological processes. In addition, alterations in
protein glycosylation have been related to different diseases, as well as may affect the …

Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry

P Ramachandran, P Boontheung, Y Xie… - Journal of proteome …, 2006 - ACS Publications
Glycoproteins make up a major and important part of the salivary proteome and play a vital
role in maintaining the health of the oral cavity. Because changes in the physiological state …

Lectin-based structural glycomics: glycoproteomics and glycan profiling

J Hirabayashi - Glycoconjugate journal, 2004 - Springer
Structural glycomics (SG) plays a fundamental part of concurrent glycobiology aiming at
comprehensive elucidation of glycan functions (ie, functional glycomics) in the context of …

Plasma glycoprotein profiling for colorectal cancer biomarker identification by lectin glycoarray and lectin blot

Y Qiu, TH Patwa, L Xu, K Shedden… - Journal of proteome …, 2008 - ACS Publications
Colorectal cancer (CRC) remains a major worldwide cause of cancer-related morbidity and
mortality largely due to the insidious onset of the disease. The current clinical procedures …