In recent years, a large number of circRNAs have been identified in mammalian cells with
high-throughput sequencing technologies and bioinformatics. The aberrant expression of …

Like most solid tumours, the microenvironment of epithelial-derived gastric adenocarcinoma
(GAC) consists of a variety of stromal cell types, including fibroblasts, and neuronal …

Background Relevant studies focusing on epidemiological of profiles hypertensive disorders
of pregnancy from global data that report the cause-specific prevalence and trends of …

Abstract N6-methyladenosine (m6A) is the most prevalent internal RNA modification in
mammals that regulates homeostasis and function of modified RNA transcripts. Here, we …

Gastric cancers, with gastric adenocarcinoma (GAC) as the most common histological type,
impose a considerable global health burden. Although the screening strategies for early …

Besides its important role in embryonic development and homeostatic self-renewal in adult
tissues, Wnt/β-catenin signaling exerts both anti-inflammatory and proinflammatory …

Single-cell transcriptomic profiles analysis has proposed new insights for understanding the
behavior of human gastric cancer (GC). GC offers a unique model of intratumoral …

Complement is operative in not only the extracellular but also the intracellular milieu.
However, little is known about the role of complement activation inside tumor cells. Here, we …

While the incidence of gastric cancer has decreased worldwide in recent decades, the
incidence of signet-ring cell carcinoma (SRCC) is rising. SRCC has a specific epidemiology …

The canonical Wnt/β-catenin signaling pathway, an important modulator of progenitor cell
proliferation and differentiation, is highly regulated for the maintenance of critical biological …