Clinical response in patients treated with once-monthly paliperidone palmitate: analysis of a therapeutic drug monitoring (TDM) database

G Schoretsanitis, E Haen, D Piacentino… - European Archives of …, 2021 - Springer
To investigate pharmacokinetic correlates of clinical response in patients treated with once-
monthly paliperidone palmitate (PP1M) injections at steady state. Plasma concentrations …

Pharmacokinetic Correlates of Once-Monthly Paliperidone Palmitate-Related Adverse Drug Reactions

G Schoretsanitis, E Haen, D Piacentino, A Conca… - Clinical …, 2021 - Springer
Objective The objective of this study was to investigate associations between
pharmacokinetic correlates and once-monthly paliperidone palmitate (PP1M)-related …

ADCK1 activates the β-catenin/TCF signaling pathway to promote the growth and migration of colon cancer cells

Y Ji, Y Liu, C Sun, L Yu, Z Wang, X Du, W Yang… - Cell Death & …, 2021 - nature.com
As a result of mutations in the upstream components of the Wnt/β-catenin signaling pathway,
this cascade is abnormally activated in colon cancer. Hence, identifying the activation …

Ethnic Differences in Antipsychotic Response: What Genetic Variation Does and Does Not Tell Us

RL Moster - Current Behavioral Neuroscience Reports, 2023 - Springer
Abstract Purpose of Review This review will discuss the current state of the
pharmacogenomics and pharmacogenetics of antipsychotic response in order to relate …

Fatal and life-threatening ADRs associated with paliperidone palmitate: an observational study in the French pharmacovigilance database

D Boels, J Mahé, A Olry, A Citterio-Quentin… - Clinical …, 2021 - Taylor & Francis
Introduction Paliperidone palmitate (PP), a long‐acting intramuscular formulation of
paliperidone, has been marketed in Europe within the last 10 years and provides an …

Death following an intramuscular injection of paliperidone: A case report

G Drevin, B Ripault, JB Ballot-Ragaru, E Bonnot… - … Analytique et Clinique, 2020 - Elsevier
Summary Paliperidone (9-hydroxyrisperidone), the primary active metabolite of risperidone,
is a benzisoxazole derivative of the second-generation antipsychotics. Paliperidone …

Generazione di cellule ADCK1 knock-out attraverso la tecnica CRISPR/Cas9

S ZAMPIERI - thesis.unipd.it
Abstract Introduzione Il sistema CRISPR-Cas9 è una tecnica di editing genetico che si basa
sull'utilizzo di una guida a singolo filamento di RNA (single-guide RNA, sgRNA) specifica …