Anticancer plants: A review of the active phytochemicals, applications in animal models, and regulatory aspects

T Khan, M Ali, A Khan, P Nisar, SA Jan, S Afridi… - Biomolecules, 2019 - mdpi.com
The rising burden of cancer worldwide calls for an alternative treatment solution. Herbal
medicine provides a very feasible alternative to western medicine against cancer. This …

Research progress of polycyclic polyprenylated acylphloroglucinols

XW Yang, RB Grossman, G Xu - Chemical reviews, 2018 - ACS Publications
Polycyclic polyprenylated acylphloroglucinols (PPAPs) are a class of hybrid natural products
sharing the mevalonate/methylerythritol phosphate and polyketide biosynthetic pathways …

Lipoxygenase inhibition by plant extracts

M Lončarić, I Strelec, T Moslavac, D Šubarić, V Pavić… - Biomolecules, 2021 - mdpi.com
Lipoxygenases are widespread enzymes that catalyze oxidation of polyunsaturated fatty
acids (linoleic, linolenic, and arachidonic acid) to produce hydroperoxides. Lipoxygenase …

Structural diversity and bioactivities of natural benzophenones

SB Wu, C Long, EJ Kennelly - Natural product reports, 2014 - pubs.rsc.org
Covering: from 1998 to early 2014 Natural benzophenones are a class of compounds
consisting of more than 300 members, which exhibit great structural diversity and bioactive …

Natural flavonoids effectively block the CD81 receptor of hepatocytes and inhibit HCV infection: A computational drug development approach

D Dey, P Biswas, P Paul, S Mahmud, TI Ema… - Molecular Diversity, 2023 - Springer
Hepatitis C virus (HCV) infection is a major public health concern, and almost two million
people are infected per year globally. This is occurred by the diverse spectrum of viral …

An in-silico identification of potential flavonoids against kidney fibrosis targeting TGFβR-1

MDH Rahman, P Biswas, D Dey, MA Hannan… - Life, 2022 - mdpi.com
Fibrosis is a hallmark of progressive kidney diseases. The overexpression of profibrotic
cytokine, namely transforming growth factor β (TGF-β) due to excessive inflammation and …

Alpha-mangostin-rich extracts from mangosteen pericarp: optimization of green extraction protocol and evaluation of biological activity

A Ghasemzadeh, HZE Jaafar, A Baghdadi… - Molecules, 2018 - mdpi.com
Since α-mangostin in mangosteen fruits was reported to be the main compound able to
provide natural antioxidants, the microwave-assisted extraction process to obtain high …

Pharmacological Activity of Garcinia indica (Kokum): An Updated Review

SH Lim, HS Lee, CH Lee, CI Choi - Pharmaceuticals, 2021 - mdpi.com
Garcinia indica (commonly known as kokum), belonging to the Clusiaceae family
(mangosteen family), is a tropical evergreen tree distributed in certain regions of India. It has …

Phytochemicals and medicinal properties of indigenous tropical fruits with potential for commercial development

HE Khoo, A Azlan, KW Kong… - … and Alternative Medicine, 2016 - Wiley Online Library
Hundreds of fruit‐bearing trees are native to Southeast Asia, but many of them are
considered as indigenous or underutilized. These species can be categorized as …

Garcinol exhibits anti-neoplastic effects by targeting diverse oncogenic factors in tumor cells

V Aggarwal, HS Tuli, J Kaur, D Aggarwal, G Parashar… - Biomedicines, 2020 - mdpi.com
Garcinol, a polyisoprenylated benzophenone, is the medicinal component obtained from
fruits and leaves of Garcinia indica (G. indica) and has traditionally been extensively used …