This report issues a call for urgent action to combat the growing epidemic of obesity, which
now affects developing and industrialized countries alike. Adopting a public health …

The present thesis is based on 14 original articles published in international journals (I-XIV,
see page 8) and a summarizing review. The thesis deals with the physiological demands of …

Background The gut microbiota is now known to play an important role contributing to
inflammatory-based chronic diseases. This study examined intestinal integrity/inflammation …

Endurance exercise training studies frequently show modest changes in VO2max with
training and very limited responses in some subjects. By contrast, studies using interval …

Background In order to implement running to promote physical activity, it is essential to
quantify the extent to which running improves health. Objective The aim was to summarise …

Endurance exercise training results in profound adaptations of the cardiorespiratory and
neuromuscular systems that enhance the delivery of oxygen from the atmosphere to the …

We examined the hypothesis that an excess accumulation of intramuscular lipid (IMCL) is
associated with insulin resistance and that this may be mediated by the oxidative capacity of …

The purpose of this investigation was to validate that in vivo measurement of skeletal muscle
attenuation (MA) with computed tomography (CT) is associated with muscle lipid content …

In elite outfield players, the average work rate during a soccer match, as estimated from
variables such as heart rate, is approximately 70% of maximal oxygen uptake (max). This …

Measures of substrate oxidation have traditionally been calculated from indirect calorimetry
measurements using stoichiometric equations. Although this has proven to be a solid …