Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

Significance: Protein S-nitrosylation, the oxidative modification of cysteine by nitric oxide
(NO) to form protein S-nitrosothiols (SNOs), mediates redox-based signaling that conveys, in …

Ammonia-oxidizing archaea are ubiquitous in marine and terrestrial environments and now
thought to be significant contributors to carbon and nitrogen cycling. The isolation of …

Oxidants are produced as a by-product of aerobic metabolism, and organisms ranging from
prokaryotes to mammals have evolved with an elaborate and redundant complement of …

Stress proteins located in the cytosol or endoplasmic reticulum (ER) maintain cell
homeostasis and afford tolerance to severe insults,,. In neurodegenerative diseases, several …

S-Nitrosylation, the redox-based modification of Cys thiol side chains by nitric oxide, is a
common mechanism in signal transduction. Dysregulated S-nitrosylation contributes to a …

S-glutathionylation and S-nitrosylation are reversible post-translational modifications on the
cysteine thiol groups of proteins, which occur in cells under physiological conditions and …

Protein disulfide isomerase (PDI), is a member of the thioredoxin superfamily of redox
proteins. PDI has three catalytic activities including, thiol-disulfide oxireductase, disulfide …

Nitric oxide acts substantially in cellular signal transduction through stimulus-coupled S-
nitrosylation of cysteine residues. The mechanisms that might subserve protein …

Nitric oxide participates in cellular signal transduction largely through S-nitrosylation of
allosteric and active-site cysteine thiols within proteins, forming S-nitroso-proteins (SNO …