A global assessment of eye health and quality of life: a systematic review of systematic reviews

L Assi, F Chamseddine, P Ibrahim… - JAMA …, 2021 - jamanetwork.com
Importance More than 1 billion people worldwide have vision impairment or blindness from
potentially preventable or correctable causes. Quality of life, an important measure of …

[HTML][HTML] Polymeric implants for the treatment of intraocular eye diseases: trends in biodegradable and non-biodegradable materials

P García-Estrada, MA García-Bon, EJ López-Naranjo… - Pharmaceutics, 2021 - mdpi.com
Intraocular/Intravitreal implants constitute a relatively new method to treat eye diseases
successfully due to the possibility of releasing drugs in a controlled and prolonged way. This …

[HTML][HTML] Effect of an injectable fluocinolone acetonide insert on recurrence rates in chronic noninfectious uveitis affecting the posterior segment: twelve-month results

GJ Jaffe, CS Foster, CE Pavesio, DA Paggiarino… - Ophthalmology, 2019 - Elsevier
Purpose To assess the safety and efficacy of an intravitreal fluocinolone acetonide (FA)
insert to manage inflammation associated with chronic noninfectious posterior uveitis …

[HTML][HTML] Recent developments in HLA B27 anterior uveitis

D Wakefield, D Clarke, P McCluskey - Frontiers in Immunology, 2021 - frontiersin.org
There has been steady progress in understanding the pathogenesis, clinical features, and
effective treatment of acute anterior uveitis (AU) over the past 5 years. Large gene wide …

Simultaneous co-delivery of neuroprotective drugs from multi-loaded PLGA microspheres for the treatment of glaucoma

A Arranz-Romera, BM Davis, I Bravo-Osuna… - Journal of Controlled …, 2019 - Elsevier
Glaucoma is a multifactorial neurodegenerative disorder and one of the leading causes of
irreversible blindness globally and for which intraocular pressure is the only modifiable risk …

Management of bacterial postoperative endophthalmitis and the role of vitrectomy

B Clarke, TH Williamson, G Gini, B Gupta - Survey of Ophthalmology, 2018 - Elsevier
Management of postoperative bacterial endophthalmitis was explored in the
Endophthalmitis Vitrectomy Study 37 in 1995, which has underpinned the core protocols in …

[HTML][HTML] Network pharmacology-based identification of the key mechanism of Qinghuo Rougan Formula acting on uveitis

C Jing, Z Sun, X Xie, X Zhang, S Wu, K Guo… - Biomedicine & …, 2019 - Elsevier
Abstract Background Qinghuo Rougan Formula (QHRGF) is a traditional Chinese medicine
(TCM) that has been widely apllied to treat uveitis for several decades. However, the …

Glucocorticoid therapy and ocular hypertension

A Dibas, T Yorio - European journal of pharmacology, 2016 - Elsevier
The projected number of people who will develop age-related macular degeneration in
estimated at 2020 is 196 million and is expected to reach 288 million in 2040. Also, the …

Evaluation of systemic immune-inflammation index level as a novel marker for severity of noninfectious uveitis

BE Kurtul, AI Cakmak, A Elbeyli, SC Ozcan… - International …, 2021 - Springer
Purpose To evaluate the association of systemic immune-inflammation index (SII) levels,
neutrophil/lymphocyte ratio (NLR), and platelet/lymphocyte ratio (PLR) with severity of …

Dexamethasone Degradation in Aqueous Medium and Implications for Correction of In Vitro Release from Sustained Release Delivery Systems

B Matter, A Ghaffari, D Bourne, Y Wang, S Choi… - AAPS …, 2019 - Springer
The in vitro drug release in an aqueous medium is a critical performance metric for a
sustained release drug product. During long-term release studies, drugs may degrade in the …