Malaria is one of the main health problems facing developing countries today. At present,
preventative and treatment strategies are continuously hampered by the issues of the ever …

Editor's Note: As an acute condition quickly associated with multiple chronic susceptibilities,
COVID-19 has rekindled interest in, and controversy about, the potential role of the host in …

Background Plasmodium falciparum can cause a diffuse encephalopathy known as cerebral
malaria (CM), a major contributor to malaria associated mortality. Despite treatment …

Proinflammatory cytokines are involved in clearance of Plasmodium falciparum, and very
high levels of these cytokines have been implicated in the pathogenesis of severe malaria …

Cerebral malaria is a severe multifactorial condition associated with the interaction of high
numbers of infected erythrocytes to human brain endothelium without invasion into the brain …

Background Tumour necrosis factor-alpha (TNF-α) levels are reportedly altered during
malaria. In this systematic review and meta-analysis, we aimed to collect and compare data …

Reorganization of host red blood cells by the malaria parasite Plasmodium falciparum
enables their sequestration via attachment to the microvasculature. This artificially increases …

Malaria continues to exert a tremendous health burden on human populations, reflecting
astonishingly successful adaptations of the causative Plasmodium parasites. We discuss …

Case fatality rates for severe malaria remain high even in the best clinical settings because
antimalarial drugs act against the parasite without alleviating life-threatening inflammation …

Babesia rossi infection causes a severe inflammatory response in the dog, which is the
result of the balance between pro-and anti-inflammatory cytokine secretion. The aim of this …