Role of insulin in health and disease: an update

MS Rahman, KS Hossain, S Das, S Kundu… - International journal of …, 2021 - mdpi.com
Insulin is a polypeptide hormone mainly secreted by β cells in the islets of Langerhans of the
pancreas. The hormone potentially coordinates with glucagon to modulate blood glucose …

[HTML][HTML] Plants secondary metabolites as blood glucose-lowering molecules

MB Shehadeh, GARY Suaifan, AM Abu-Odeh - Molecules, 2021 - mdpi.com
Recently, significant advances in modern medicine and therapeutic agents have been
achieved. However, the search for effective antidiabetic drugs is continuous and …

New β-carboline derivatives as potential α-glucosidase inhibitor: Synthesis and biological activity evaluation

J Lin, D Xiao, L Lu, B Liang, Z Xiong, X Xu - Journal of Molecular Structure, 2023 - Elsevier
Abstract α-Glucosidase is an important therapeutic target of diabetes mellitus. To find potent
α-glucosidase inhibitors, thirty-one β-carboline derivatives containing piperazine moieties …

Chemical structure and inhibition on α-glucosidase of polysaccharides from corn silk by fractional precipitation

Y Jia, Z Xue, Y Wang, Y Lu, R Li, N Li, Q Wang… - Carbohydrate …, 2021 - Elsevier
Aimed to explore different corn silk polysaccharide (CSP) fractions derived by ethanol
precipitation on the physicochemical properties and biological activities, four fractions …

Phytochemical Characterization, Functional Nutrition, and Anti-Diabetic Potentials of Leptadenia hastata (pers) Decne Leaves: In Silico and In Vitro Studies

IF Chukwuma, FN Nworah, VO Apeh… - … and Biology Insights, 2022 - journals.sagepub.com
The geometrical increase in diabetes mellitus (DM) and the undesirable side effects of
synthetic drugs have intensified efforts to search for an effective and safe anti-diabetic …

Alkaloidal phytoconstituents for diabetes management: exploring the unrevealed potential

T Behl, A Gupta, M Albratty, A Najmi, AM Meraya… - Molecules, 2022 - mdpi.com
The main characteristic feature of diabetes mellitus is the disturbance of carbohydrate, lipid,
and protein metabolism, which results in insulin insufficiency and can also lead to insulin …

New insights into the bioactive polysaccharides, proteins, and triterpenoids isolated from bitter melon (Momordica charantia) and their relevance for nutraceutical and …

AFM Bora, KJEP Kouame, X Li, L Liu, Y Pan - International Journal of …, 2023 - Elsevier
The recent trend in infectious diseases and chronic disorders has dramatically increased
consumers' interest in functional foods. As a result, the research of bioactive ingredients with …

Design, synthesis, and antifungal evaluation of cryptolepine derivatives against phytopathogenic fungi

YJ Chen, H Liu, SY Zhang, H Li, KY Ma… - Journal of Agricultural …, 2021 - ACS Publications
Inspired by the widely antiphytopathogenic application of diversified derivatives from natural
sources, cryptolepine and its derivatives were subsequently designed, synthesized, and …

Potential antidiabetic phytochemicals in plant roots: A review of in vivo studies

H Ardalani, F Hejazi Amiri, A Hadipanah… - Journal of Diabetes & …, 2021 - Springer
Background Medicinal plants are used to treat various disorders, including diabetes,
globally in a range of formulations. While attention has mainly been on the aerial plant parts …

The compositional aspects of edible flowers as an emerging horticultural product

EO Pires Jr, F Di Gioia, Y Rouphael, ICFR Ferreira… - Molecules, 2021 - mdpi.com
Edible flowers are becoming very popular, as consumers are seeking healthier and more
attractive food products that can improve their diet aesthetics and diversify their dietary …