Current challenges of iPSC-based disease modeling and therapeutic implications
MX Doss, A Sachinidis - Cells, 2019 - mdpi.com
Induced pluripotent stem cell (iPSC)-based disease modelling and the cell replacement
therapy approach have proven to be very powerful and instrumental in biomedical research …
therapy approach have proven to be very powerful and instrumental in biomedical research …
Cellular senescence: from mechanisms to current biomarkers and senotherapies
V Lucas, C Cavadas, CA Aveleira, V Hook - Pharmacological Reviews, 2023 - Elsevier
An increase in life expectancy in developed countries has led to a surge of chronic aging-
related diseases. In the last few decades, several studies have provided evidence of the …
related diseases. In the last few decades, several studies have provided evidence of the …
A comprehensive review for breast histopathology image analysis using classical and deep neural networks
Breast cancer is one of the most common and deadliest cancers among women. Since
histopathological images contain sufficient phenotypic information, they play an …
histopathological images contain sufficient phenotypic information, they play an …
Anti-senescent drug screening by deep learning-based morphology senescence scoring
D Kusumoto, T Seki, H Sawada, A Kunitomi… - Nature …, 2021 - nature.com
Advances in deep learning technology have enabled complex task solutions. The accuracy
of image classification tasks has improved owing to the establishment of convolutional …
of image classification tasks has improved owing to the establishment of convolutional …
The application of convolutional neural network to stem cell biology
D Kusumoto, S Yuasa - Inflammation and regeneration, 2019 - Springer
Induced pluripotent stem cells (iPSC) are one the most prominent innovations of medical
research in the last few decades. iPSCs can be easily generated from human somatic cells …
research in the last few decades. iPSCs can be easily generated from human somatic cells …
Single-cell cytometry via multiplexed fluorescence prediction by label-free reflectance microscopy
Traditional imaging cytometry uses fluorescence markers to identify specific structures but is
limited in throughput by the labeling process. We develop a label-free technique that …
limited in throughput by the labeling process. We develop a label-free technique that …
Artificial intelligence for microscopy: what you should know
L von Chamier, RF Laine… - Biochemical Society …, 2019 - portlandpress.com
Abstract Artificial Intelligence based on Deep Learning (DL) is opening new horizons in
biomedical research and promises to revolutionize the microscopy field. It is now …
biomedical research and promises to revolutionize the microscopy field. It is now …
Basic of machine learning and deep learning in imaging for medical physicists
L Manco, N Maffei, S Strolin, S Vichi, L Bottazzi… - Physica Medica, 2021 - Elsevier
The manuscript aims at providing an overview of the published algorithms/automation tool
for artificial intelligence applied to imaging for Healthcare. A PubMed search was performed …
for artificial intelligence applied to imaging for Healthcare. A PubMed search was performed …
Moving towards induced pluripotent stem cell-based therapies with artificial intelligence and machine learning
C Coronnello, MG Francipane - Stem Cell Reviews and Reports, 2022 - Springer
The advent of induced pluripotent stem cell (iPSC) technology, which allows to transform
one cell type into another, holds the promise to produce therapeutic cells and organs on …
one cell type into another, holds the promise to produce therapeutic cells and organs on …
Deep learning neural networks highly predict very early onset of pluripotent stem cell differentiation
A Waisman, A La Greca, AM Möbbs, MA Scarafía… - Stem cell reports, 2019 - cell.com
Deep learning is a significant step forward for developing autonomous tasks. One of its
branches, computer vision, allows image recognition with high accuracy thanks to the use of …
branches, computer vision, allows image recognition with high accuracy thanks to the use of …