The fascination and fear of snakes dates back to time immemorial, with the first scientific
treatise on snakebite envenoming, the Brooklyn Medical Papyrus, dating from ancient Egypt …

Advances in the last decade combining transcriptomics with established proteomics
methods have made possible rapid identification and quantification of protein families in …

A deep understanding of the composition of venoms and of the principles governing the
evolution of venomous systems is of applied importance for exploring the enormous …

Toxins from Bothrops venoms targeting hemostasis are responsible for a broad range of
clinical and biological syndromes including local and systemic bleeding, incoagulability …

In Latin America, Bothrops snakes account for most snake bites in humans, and the
recommended treatment is administration of multispecific Bothrops antivenom (SAB–soro …

Bothrops atrox snakes are mostly endemic of the Amazon rainforest and is certainly the
South American pit viper responsible for most of the snakebites in the region. The …

Snake venoms present a great diversity of pharmacologically active compounds that may be
applied as research and biotechnological tools, as well as in drug development and …

Snake envenoming is a globally neglected public health problem. Antivenoms produced
using animal hyperimmune plasma remain the standard therapy for snakebites. Although …

Snake venom L-amino acid oxidases (LAAOs) are flavoproteins, which perform diverse
biological activities in the victim such as edema, myotoxicity and cytotoxicity, contributing to …

Comparisons between venoms from snakes kept under captivity or collected at the natural
environment are of fundamental importance in order to obtain effective antivenoms to treat …