MicroRNAs (miRNAs) are essential post-transcriptional gene regulators involved in various
neuronal and non-neuronal cell functions and play a key role in pathological conditions …

Amyotrophic lateral sclerosis (ALS) is a fatal neurological disease, which is characterized by
the degeneration of motor neurons in the motor cortex and the spinal cord and subsequently …

The noncoding genome is substantially larger than the protein-coding genome but has been
largely unexplored by genetic association studies. Here, we performed region-based rare …

Amyotrophic lateral sclerosis (ALS) is a relentless neurodegenerative disease of the human
motor neuron system, where variability in progression rate limits clinical trial efficacy …

Alzheimer's disease (AD), Parkinson's disease (PD), and Amyotrophic Lateral Sclerosis
(ALS) are representative neurodegenerative diseases (NDs) characterized by degeneration …

RNA metabolism is central to cellular physiopathology. Almost all the molecular pathways
underpinning biological processes are affected by the events governing the RNA life cycle …

In the brain, microRNAs (miRNAs) are believed to play a role in orchestrating synaptic
plasticity at a higher level by acting as an additional mechanism of translational regulation …

Characterizing the diverse cell types that make up the nervous system is essential for
understanding how the nervous system is structured and ultimately how it functions. The …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
the loss of motor neurons (MNs). There are no effective treatments and patients usually die …

Disruption of homeostatic microRNA (miRNA) expression levels is known to cause human
neuropathology. However, the gene regulatory and phenotypic effects of altering a miRNA's …