Bioinorganic chemistry of Alzheimer's disease
KP Kepp - Chemical reviews, 2012 - ACS Publications
Alzheimer's disease (AD) 1− 3 is the most common form of dementia (estimated∼ 50− 60%
of all cases), associated with loss of memory (in particular episodic memory), cognitive …
of all cases), associated with loss of memory (in particular episodic memory), cognitive …
Mercury toxicity and neurodegenerative effects
A Carocci, N Rovito, MS Sinicropi, G Genchi - Reviews of environmental …, 2014 - Springer
Neurodegeneration is a broadly defined term that describes the loss of neuronal structure
and function, and produces disorders known as neurodegenerative diseases. A common …
and function, and produces disorders known as neurodegenerative diseases. A common …
[HTML][HTML] Decreased brain levels of vitamin B12 in aging, autism and schizophrenia
Y Zhang, NW Hodgson, MS Trivedi, HM Abdolmaleky… - PloS one, 2016 - journals.plos.org
Many studies indicate a crucial role for the vitamin B12 and folate-dependent enzyme
methionine synthase (MS) in brain development and function, but vitamin B12 status in the …
methionine synthase (MS) in brain development and function, but vitamin B12 status in the …
How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis
R Deth, C Muratore, J Benzecry, VA Power-Charnitsky… - Neurotoxicology, 2008 - Elsevier
Recently higher rates of autism diagnosis suggest involvement of environmental factors in
causing this developmental disorder, in concert with genetic risk factors. Autistic children …
causing this developmental disorder, in concert with genetic risk factors. Autistic children …
Aluminum vaccine adjuvants: are they safe?
L Tomljenovic, CA Shaw - Current medicinal chemistry, 2011 - ingentaconnect.com
Aluminum is an experimentally demonstrated neurotoxin and the most commonly used
vaccine adjuvant. Despite almost 90 years of widespread use of aluminum adjuvants …
vaccine adjuvant. Despite almost 90 years of widespread use of aluminum adjuvants …
Does inorganic mercury play a role in Alzheimer's disease? A systematic review and an integrated molecular mechanism
Mercury is one of the most toxic substances known to humans. It has been introduced into
the human environment and has also been widely used in medicine. Since circumstantial …
the human environment and has also been widely used in medicine. Since circumstantial …
Evidence of toxicity, oxidative stress, and neuronal insult in autism
JK Kern, AM Jones - … of Toxicology and Environmental Health, Part …, 2006 - Taylor & Francis
According to the Autism Society of America, autism is now considered to be an epidemic.
The increase in the rate of autism revealed by epidemiological studies and government …
The increase in the rate of autism revealed by epidemiological studies and government …
Early thimerosal exposure and neuropsychological outcomes at 7 to 10 years
WW Thompson, C Price, B Goodson… - … England Journal of …, 2007 - Mass Medical Soc
Background It has been hypothesized that early exposure to thimerosal, a mercury-
containing preservative used in vaccines and immune globulin preparations, is associated …
containing preservative used in vaccines and immune globulin preparations, is associated …
[HTML][HTML] Incorporating epigenetic data into the risk assessment process for the toxic metals arsenic, cadmium, chromium, lead, and mercury: strategies and challenges
PD Ray, A Yosim, RC Fry - Frontiers in genetics, 2014 - frontiersin.org
Exposure to toxic metals poses a serious human health hazard based on ubiquitous
environmental presence, the extent of exposure, and the toxicity and disease states …
environmental presence, the extent of exposure, and the toxicity and disease states …
[HTML][HTML] Fragile X and autism: Intertwined at the molecular level leading to targeted treatments
R Hagerman, G Hoem, P Hagerman - Molecular autism, 2010 - Springer
Fragile X syndrome (FXS) is caused by an expanded CGG repeat (> 200 repeats) in the
5'untranslated portion of the fragile mental retardation 1 gene (FMR1), leading to deficiency …
5'untranslated portion of the fragile mental retardation 1 gene (FMR1), leading to deficiency …