In this review, the history of boron's early use in drugs, and the history of the use of boron
functional groups in medicinal chemistry applications are discussed. This includes …

Boron cluster compounds are inorganic compounds with chemical compositions and
structures vastly different from those of organic compounds, albeit with the ability to form a …

A new group of nido-carboranyl derivatives of natural (S)-amino acids containing from 9 to
18 boron atoms was obtained in good yields as a result of acylation of 3-amino-1, 2-dicarba …

Derivatives of dicarba-closo-dodecaboranes and dicarba-nido-undecaboranes (carboranes)
are of increasing interest for modern medicinal chemistry and materials science. The …

Abstract “There's plenty of room at the bottom”(Richard Feynman, 1959): an invitation for
(metalla) carboranes to enter the (new) field of nanomedicine. For two decades, the number …

Abstract The development of 1, 8-naphthalimide derivatives as DNA-targeting anticancer
agents is a rapidly growing area and has resulted in several derivatives entering into clinical …

Pseudomonas aeruginosa is an opportunistic human pathogen that has become a
nosocomial health problem worldwide. The pathogen has multiple drug removal and …

We synthesized a series of novel 3-carboranyl-1, 8-naphthalimide derivatives, mitonafide
and pinafide analogs, using click chemistry, reductive amination and amidation reactions …

Metallacarboranes are anionic boron clusters with high affinity to serum albumin, ability to
cross biological membranes, and no apparent toxicity in vitro and in vivo. Thus, conjugation …

Tuberculosis (TB) is a severe infectious disease with high mortality and morbidity. The
emergence of drug-resistant TB has increased the challenge to eliminate this disease …