Sudden unexpected death in epilepsy: epidemiology, mechanisms, and prevention

O Devinsky, DC Hesdorffer, DJ Thurman… - The Lancet …, 2016 - thelancet.com
Sudden unexpected death in epilepsy (SUDEP) can affect individuals of any age, but is most
common in younger adults (aged 20–45 years). Generalised tonic-clonic seizures are the …

[HTML][HTML] The consequences of refractory epilepsy and its treatment

KD Laxer, E Trinka, LJ Hirsch, F Cendes, J Langfitt… - Epilepsy & behavior, 2014 - Elsevier
Abstract Seizures in some 30% to 40% of patients with epilepsy fail to respond to
antiepileptic drugs or other treatments. While much has been made of the risks of new drug …

Practice guideline summary: sudden unexpected death in epilepsy incidence rates and risk factors: report of the Guideline Development, Dissemination, and …

C Harden, T Tomson, D Gloss, J Buchhalter, JH Cross… - Neurology, 2017 - AAN Enterprises
Objective: To determine the incidence rates of sudden unexpected death in epilepsy
(SUDEP) in different epilepsy populations and address the question of whether risk factors …

Epilepsy: new advances

SL Moshé, E Perucca, P Ryvlin, T Tomson - The Lancet, 2015 - thelancet.com
Epilepsy affects 65 million people worldwide and entails a major burden in seizure-related
disability, mortality, comorbidities, stigma, and costs. In the past decade, important advances …

Incidence and mechanisms of cardiorespiratory arrests in epilepsy monitoring units (MORTEMUS): a retrospective study

P Ryvlin, L Nashef, SD Lhatoo, LM Bateman… - The Lancet …, 2013 - thelancet.com
Background Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in
people with chronic refractory epilepsy. Very rarely, SUDEP occurs in epilepsy monitoring …

Sudden unexpected death in epilepsy: assessing the public health burden

DJ Thurman, DC Hesdorffer, JA French - Epilepsia, 2014 - Wiley Online Library
Objective There is not yet a clear consensus on the incidence of sudden unexpected death
in epilepsy (SUDEP) or the extent of its burden on public health. In this systematic review …

The burden of premature mortality of epilepsy in high‐income countries: a systematic review from the Mortality Task Force of the International League Against Epilepsy

DJ Thurman, G Logroscino, E Beghi, WA Hauser… - …, 2017 - Wiley Online Library
Since previous reviews of epidemiologic studies of premature mortality among people with
epilepsy were completed several years ago, a large body of new evidence about this subject …

Mortality in Dravet syndrome

MS Cooper, A Mcintosh, DE Crompton, JM McMahon… - Epilepsy research, 2016 - Elsevier
We measured the mortality rate and the rate of Sudden Unexpected Death in Epilepsy
(SUDEP) in Dravet Syndrome (DS). We studied a cohort of 100 consecutively recruited …

Unifying the definitions of sudden unexpected death in epilepsy

L Nashef, EL So, P Ryvlin, T Tomson - Epilepsia, 2012 - Wiley Online Library
Sudden unexpected death in epilepsy (SUDEP) is a category of death in people with
epilepsy occurring in the absence of a known structural cause of death and is most likely …

Cannabinoids in treatment-resistant epilepsy: a review

BK O'Connell, D Gloss, O Devinsky - Epilepsy & Behavior, 2017 - Elsevier
Abstract Treatment-resistant epilepsy (TRE) affects 30% of epilepsy patients and is
associated with severe morbidity and increased mortality. Cannabis-based therapies have …