Clinical manifestations and immune response to tuberculosis

ML Carabalí-Isajar, OH Rodríguez-Bejarano… - World Journal of …, 2023 - Springer
Tuberculosis is a far-reaching, high-impact disease. It is among the top ten causes of death
worldwide caused by a single infectious agent; 1.6 million tuberculosis-related deaths were …

[HTML][HTML] Adjuvants approved for human use: What do we know and what do we need to know for designing good adjuvants?

C Reyes, MA Patarroyo - European Journal of Pharmacology, 2023 - Elsevier
Adjuvants represent one of the most significant biotechnological solutions regarding vaccine
development, thereby broadening the amount of candidates which can now be used and …

[HTML][HTML] Micro-and nanoformulations of antibiotics against Brucella

M Alavi, A Nokhodchi - Drug Discovery Today, 2023 - Elsevier
Highlights•Combination therapy and targeted delivery systems reduce bacterial counts.•
Nanoformulation improves the efficacy of treatment in both the chronic and acute …

[HTML][HTML] Evasion of host defense by Brucella

J Yang, Y Wang, Y Hou, M Sun, T Xia, X Wu - Cell Insight, 2023 - Elsevier
Brucella, an adept intracellular pathogen, causes brucellosis, a zoonotic disease leading to
significant global impacts on animal welfare and the economy. Regrettably, there is currently …

A Comprehensive review on bacterial vaccines combating antimicrobial resistance in poultry

MS Islam, MT Rahman - Vaccines, 2023 - mdpi.com
Bacterial vaccines have become a crucial tool in combating antimicrobial resistance (AMR)
in poultry. The overuse and misuse of antibiotics in poultry farming have led to the …

An integrated in silico approach for the identification of novel potential drug target and chimeric vaccine against Neisseria meningitides strain 331401 serogroup X by …

M Asad, A Hassan, W Wang, WB Alonazi… - Computers in Biology …, 2024 - Elsevier
Neisseria meningitidis, commonly known as the meningococcus, leads to substantial illness
and death among children and young adults globally, revealing as either epidemic or …

Antibacterial properties, biocompatibility and superelastic behavior of Au-cysteine-gentamicin-functionalized Ti–Zr–Nb alloy

TO Teplyakova, AS Konopatsky, TM Iakimova… - Materials Today …, 2024 - Elsevier
Abstract Superelastic Ti–18Zr–15Nb alloy capable of mimicking the mechanical behavior of
a bone tissue is a promising biomaterial but suffers from the lack of antibacterial properties …

The Love and Hate Relationship between T5SS and Other Secretion Systems in Bacteria

Y Luo, Z Chen, S Lian, X Ji, C Zhu, G Zhu… - International Journal of …, 2023 - mdpi.com
Bacteria have existed on Earth for billions of years, exhibiting ubiquity and involvement in
various biological activities. To ensure survival, bacteria usually release and secrete effector …

The aroA and luxS Double-Gene Mutant Strain Has Potential to Be a Live Attenuated Vaccine against Salmonella Typhimurium

W Zuo, D Yang, X Wu, B Zhang, X Wang, J Hu, J Qi… - Vaccines, 2024 - mdpi.com
Salmonella Typhimurium (S. Typhimurium) is a zoonotic pathogen posing a threat to animal
husbandry and public health. Due to the emergence of antibiotic-resistant strains, alternative …

Brucella infection and Toll-like receptors

H Yu, X Gu, D Wang, Z Wang - Frontiers in Cellular and Infection …, 2024 - frontiersin.org
Brucella consists of gram-negative bacteria that have the ability to invade and replicate in
professional and non-professional phagocytes, and its prolonged persistence in the host …