[HTML][HTML] Genetic and environmental factors associated with type 2 diabetes and diabetic vascular complications
M Murea, L Ma, BI Freedman - The review of diabetic studies: RDS, 2012 - ncbi.nlm.nih.gov
Faced with a global epidemic of type 2 diabetes (T2D), it is critical that researchers improve
our understanding of the pathogenesis of T2D and related vascular complications. These …
our understanding of the pathogenesis of T2D and related vascular complications. These …
Coronary heart disease in type 2 diabetes mellitus: genetic factors and their mechanisms, gene-gene, and gene-environment interactions in the asian populations
KA Zarkasi, NA Abdul Murad, N Ahmad… - International Journal of …, 2022 - mdpi.com
Asians are more susceptible to type 2 diabetes mellitus (T2D) and its coronary heart disease
(CHD) complications than the Western populations, possibly due to genetic factors, higher …
(CHD) complications than the Western populations, possibly due to genetic factors, higher …
Long noncoding RNA ANRIL regulates endothelial cell activities associated with coronary artery disease by up-regulating CLIP1, EZR, and LYVE1 genes
Coronary artery disease (CAD) is the leading cause of death worldwide. Long noncoding
RNAs (lncRNAs) are a class of noncoding transcripts of> 200 nucleotides and are …
RNAs (lncRNAs) are a class of noncoding transcripts of> 200 nucleotides and are …
Molecular basis of gene-gene interaction: cyclic cross-regulation of gene expression and post-GWAS gene-gene interaction involved in atrial fibrillation
Y Huang, C Wang, Y Yao, X Zuo, S Chen, C Xu… - PLoS …, 2015 - journals.plos.org
Atrial fibrillation (AF) is the most common cardiac arrhythmia at the clinic. Recent GWAS
identified several variants associated with AF, but they account for< 10% of heritability. Gene …
identified several variants associated with AF, but they account for< 10% of heritability. Gene …
The IL-33-ST2L pathway is associated with coronary artery disease in a Chinese Han population
X Tu, S Nie, Y Liao, H Zhang, Q Fan, C Xu, Y Bai… - The American Journal of …, 2013 - cell.com
The effects of interleukin-33 (IL-33) on the immune system have been clearly demonstrated;
however, in cardiovascular diseases, especially in coronary artery disease (CAD), these …
however, in cardiovascular diseases, especially in coronary artery disease (CAD), these …
Association of ApoE gene polymorphisms with serum lipid levels and the risk of type 2 diabetes mellitus in the Chinese Han population of central China
Y Zeng, S Wen, L Huan, L Xiong, B Zhong, P Wang - PeerJ, 2023 - peerj.com
Background Apolipoprotein E (ApoE) is involved in lipid transformation and metabolism.
Although some studies have examined the association between ApoE polymorphisms and …
Although some studies have examined the association between ApoE polymorphisms and …
Genomic variant in CAV1 increases susceptibility to coronary artery disease and myocardial infarction
S Chen, X Wang, J Wang, Y Zhao, D Wang, C Tan, J Fa… - Atherosclerosis, 2016 - Elsevier
Background The CAV1 gene encodes caveolin-1 expressed in cell types relevant to
atherosclerosis. Cav-1-null mice showed a protective effect on atherosclerosis under the …
atherosclerosis. Cav-1-null mice showed a protective effect on atherosclerosis under the …
[HTML][HTML] Functional rare variant in a C/EBP beta binding site in NINJ2 gene increases the risk of coronary artery disease
P Wang, Y Wang, H Peng, J Wang, Q Zheng… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Objective: NINJ2 regulates activation of vascular endothelial cells, and genome-wide
association studies showed that variants in NINJ2 confer risk to stroke. However, whether …
association studies showed that variants in NINJ2 confer risk to stroke. However, whether …
Genomic Variant in IL-37 Confers A Significant Risk of Coronary Artery Disease
D Yin, DH Naji, Y Xia, S Li, Y Bai, G Jiang, Y Zhao… - Scientific reports, 2017 - nature.com
The interleukin 1 family plays an important role in the immune and inflammatory responses.
Coronary artery disease (CAD) is a chronic inflammatory disease. However, the genetic …
Coronary artery disease (CAD) is a chronic inflammatory disease. However, the genetic …
Association of ANRIL polymorphism (rs1333049: C> G) with myocardial infarction and its pharmacogenomic role in hypercholesterolemia
Single nucleotide polymorphisms (SNPs) of non-coding RNA in the INK4 locus (ANRIL)
have been found to be associated with myocardial infarction (MI). However, the effect of …
have been found to be associated with myocardial infarction (MI). However, the effect of …