Peripheral nerve reconstruction after injury: a review of clinical and experimental therapies

D Grinsell, CP Keating - BioMed research international, 2014 - Wiley Online Library
Unlike other tissues in the body, peripheral nerve regeneration is slow and usually
incomplete. Less than half of patients who undergo nerve repair after injury regain good to …

Scaffolds for peripheral nerve repair and reconstruction

S Yi, L Xu, X Gu - Experimental neurology, 2019 - Elsevier
Trauma-associated peripheral nerve defect is a widespread clinical problem. Autologous
nerve grafting, the current gold standard technique for the treatment of peripheral nerve …

[图书][B] Nerve repair

TM Brushart - 2011 - books.google.com
Nerve Repair is a historically-based, translational review of the clinical and basic science
relevant to nerve repair and regeneration. Essential reading for a wide range of …

The evolution of neuroprosthetic interfaces

DO Adewole, MD Serruya, JP Harris… - Critical Reviews™ in …, 2016 - dl.begellhouse.com
The ideal neuroprosthetic interface permits high-quality neural recording and stimulation of
the nervous system while reliably providing clinical benefits over chronic periods. Although …

Intrathecal gene therapy rescues a model of demyelinating peripheral neuropathy

A Kagiava, I Sargiannidou… - Proceedings of the …, 2016 - National Acad Sciences
Inherited demyelinating peripheral neuropathies are progressive incurable diseases without
effective treatment. To develop a gene therapy approach targeting myelinating Schwann …

Spinal cord regeneration: where fish, frogs and salamanders lead the way, can we follow?

JF Diaz Quiroz, K Echeverri - Biochemical Journal, 2013 - portlandpress.com
Major trauma to the mammalian spinal cord often results in irreversible loss of function, ie
paralysis, and current therapies ranging from drugs, implantations of stem cells and/or …

Anisotropically conductive biodegradable scaffold with coaxially aligned carbon nanotubes for directional regeneration of peripheral nerves

S Ghosh, S Haldar, S Gupta, A Bisht… - ACS Applied Bio …, 2020 - ACS Publications
Fascicular rearrangement of an injured peripheral nerve requires reconnection of nerve
sprouts from anterior and Büngner bands from distal sides of the lesion, failing to which …

Typical and atypical properties of peripheral nerve allografts enable novel strategies to repair segmental-loss injuries

GD Bittner, JS Bushman, CL Ghergherehchi… - Journal of …, 2022 - Springer
We review data showing that peripheral nerve injuries (PNIs) that involve the loss of a nerve
segment are the most common type of traumatic injury to nervous systems. Segmental-loss …

Polyethylene glycol (PEG) and other bioactive solutions with neurorrhaphy for rapid and dramatic repair of peripheral nerve lesions by PEG-fusion

CL Ghergherehchi, M Mikesh, DR Sengelaub… - Journal of neuroscience …, 2019 - Elsevier
Background Nervous system injuries in mammals often involve transection or segmental
loss of peripheral nerves. Such injuries result in functional (behavioral) deficits poorly …

The curious ability of polyethylene glycol fusion technologies to restore lost behaviors after nerve severance

GD Bittner, DR Sengelaub, RC Trevino… - Journal of …, 2016 - Wiley Online Library
Traumatic injuries to PNS and CNS axons are not uncommon. Restoration of lost behaviors
following severance of mammalian peripheral nerve axons (PNAs) relies on regeneration by …