Poor water solubility of many drugs has emerged as one of the major challenges in the
pharmaceutical world. Polymer-based amorphous solid dispersions have been considered …

Solid-state NMR (ssNMR) spectroscopy analyzes a wide range of pharmaceutical materials
in a non-disruptive and non-invasive manner. The obtained molecular properties at …

Amorphous solid dispersion (ASD) can accelerate a project by improving dissolution rate
and solubility, offering dose escalation flexibility and excipient acceptance for toxicology …

Developments of NMR methodology to characterise the structures of molecular organic
structures are reviewed, concentrating on the previous decade of research in which density …

Amorphous solid dispersions (ASDs) have gained attention as a formulation strategy in
recent years, with the potential to improve the apparent solubility and, hence, the oral …

The main goal of a novel drug development is to obtain it with optimal physiochemical,
pharmaceutical and biological properties. Pharmaceutical companies and scientists modify …

Amorphous solid dispersions (ASDs) are a promising formulation approach to improve the
solubility, dissolution rate, and bioavailability of poorly water-soluble drugs. ASDs have …

Amorphous solid dispersions (ASDs) are single-phase amorphous systems, where drug
molecules are molecularly dispersed (dissolved) in a polymer matrix. The molecular …

Abstract Purpose Amorphous solid dispersions (ASDs) have been widely used in the
pharmaceutical industry for solubility enhancementof poorly water-soluble drugs. The …

This study reports the development of ritonavir-copovidone amorphous solid dispersions
(ASDs) and dosage forms thereof using selective laser sintering (SLS) 3-dimensional (3-D) …