Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …

Neuronal cell death occurs extensively during development and pathology, where it is
especially important because of the limited capacity of adult neurons to proliferate or be …

Apoptosis, also named programmed cell death, is a fundament process required for
morphogenetic homeostasis during early development and in pathophysiological …

The tumour suppressor gene TP53 is mutated in~ 50% of human cancers. In addition to its
function in tumour suppression, p53 also plays a major role in the response of malignant as …

Pyroptosis, apoptosis, necroptosis, and ferroptosis, which are the most well-studied
regulated cell death (RCD) pathways, contribute to the clearance of infected or potentially …

In the early 2000s, receptor-interacting serine/threonine protein kinase 1 (RIPK1), a
molecule already recognized as an important regulator of cell survival, inflammation and …

Caspase-9, a cysteine-aspartic protease known for its role as an initiator of intrinsic
apoptosis, regulates physiological cell death and pathological tissue degeneration. Its …

Animals receive environmental stimuli from neural signals in order to produce hormones that
control immune responses. Glucocorticoids (GCs) are a group of steroid hormones …

To date, numerous inorganic nanocarriers have been explored for drug delivery systems
(DDSs). However, the clinical application of inorganic formulations has often been hindered …

The mechanism by which cells undergo death determines whether dying cells trigger
inflammatory responses or remain immunologically silent. Mitochondria play a central role in …