Impact of adolescent social experiences on behavior and neural circuits implicated in mental illnesses

AR Burke, CM McCormick, SM Pellis… - … & Biobehavioral Reviews, 2017 - Elsevier
Negative social experiences during adolescence are central features for several stress-
related mental illnesses. Social play fighting behavior in rats peaks during early …

Oxytocin and vasopressin neural networks: Implications for social behavioral diversity and translational neuroscience

ZV Johnson, LJ Young - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Oxytocin-and vasopressin-related systems are present in invertebrate and vertebrate
bilaterian animals, including humans, and exhibit conserved neuroanatomical and …

Social isolation stress in adolescence, but not adulthood, produces hypersocial behavior in adult male and female C57BL/6J mice

JK Rivera-Irizarry, MJ Skelly, KE Pleil - Frontiers in behavioral …, 2020 - frontiersin.org
Chronic stress during the developmental period of adolescence increases susceptibility to
many neuropsychiatric diseases in adulthood, including anxiety, affective, and …

Effects of experimental sleep deprivation on anxiety-like behavior in animal research: Systematic review and meta-analysis

GN Pires, AG Bezerra, S Tufik, ML Andersen - … & Biobehavioral Reviews, 2016 - Elsevier
Increased acute anxiety is a commonly reported behavioral consequence of sleep
deprivation in humans. However, rodent studies conducted so far produced inconsistent …

The environmental enrichment model revisited: A translatable paradigm to study the stress of our modern lifestyle

M Rojas‐Carvajal, A Sequeira‐Cordero… - European Journal of …, 2022 - Wiley Online Library
Mounting evidence shows that physical activity, social interaction and sensorimotor
stimulation provided by environmental enrichment (EE) exert several neurobehavioural …

[HTML][HTML] Swimming exercise ameliorates mood disorder and memory impairment by enhancing neurogenesis, serotonin expression, and inhibiting apoptosis in social …

HS Park, TW Kim, SS Park, SJ Lee - Journal of Exercise …, 2020 - ncbi.nlm.nih.gov
Social isolation during adolescence is associated with anxiety, depres-sion, and memory
impairment. Exercise has been reported as a positive effect on brain function, especially …

Mitochondrial dysfunction bridges negative affective disorders and cardiomyopathy in socially isolated rats: pros and cons of fluoxetine

N Sonei, S Amiri, I Jafarian, M Anoush… - The World Journal of …, 2017 - Taylor & Francis
Objectives Depression is tightly associated with cardiovascular comorbidity and accounts for
high financial and social burden worldwide. Mitochondrial dysfunction contributes to the …

Evaluating social defeat as a model for psychopathology in adult female rodents

MB Solomon - Journal of Neuroscience Research, 2017 - Wiley Online Library
Social conflict is a predominant stressor in humans and is associated with increased risk for
developing psychological illnesses including depression and anxiety. Overwhelmingly …

Alcohol binge drinking and anxiety‐like behavior in socialized versus isolated c57bl/6j mice

O Evans, O Rodríguez‐Borillo, L Font… - Alcoholism: Clinical …, 2020 - Wiley Online Library
Background Binge alcohol drinking has been characterized as a key feature of alcoholism.
The drinking‐in‐the‐dark (DID) preclinical model, a procedure that promotes high levels of …

The role of mGluR5 on the therapeutic effects of ketamine in Wistar rats

D Gokalp, G Unal - Psychopharmacology, 2024 - Springer
Rationale Ketamine produces dissociative, psychomimetic, anxiolytic, antidepressant, and
anesthetic effects in a dose dependent manner. It has a complex mechanism of action that …