[HTML][HTML] Protein diversification through post-translational modifications, alternative splicing, and gene duplication
Proteins provide the basis for cellular function. Having multiple versions of the same protein
within a single organism provides a way of regulating its activity or developing novel …
within a single organism provides a way of regulating its activity or developing novel …
Protein phosphorylation database and prediction tools
MX Zhao, Q Chen, F Li, S Fu, B Huang… - Briefings in …, 2023 - academic.oup.com
Protein phosphorylation, one of the main protein post-translational modifications, is required
for regulating various life activities. Kinases and phosphatases that regulate protein …
for regulating various life activities. Kinases and phosphatases that regulate protein …
dbPTM in 2022: an updated database for exploring regulatory networks and functional associations of protein post-translational modifications
Protein post-translational modifications (PTMs) play an important role in different cellular
processes. In view of the importance of PTMs in cellular functions and the massive data …
processes. In view of the importance of PTMs in cellular functions and the massive data …
A Review of Machine Learning and Algorithmic Methods for Protein Phosphorylation Site Prediction
F Esmaili, M Pourmirzaei, S Ramazi… - Genomics …, 2023 - academic.oup.com
Post-translational modifications (PTMs) have key roles in extending the functional diversity
of proteins and, as a result, regulating diverse cellular processes in prokaryotic and …
of proteins and, as a result, regulating diverse cellular processes in prokaryotic and …
GPS-SUMO 2.0: an updated online service for the prediction of SUMOylation sites and SUMO-interacting motifs
Y Gou, D Liu, M Chen, Y Wei, X Huang… - Nucleic Acids …, 2024 - academic.oup.com
Small ubiquitin-like modifiers (SUMOs) are tiny but important protein regulators involved in
orchestrating a broad spectrum of biological processes, either by covalently modifying …
orchestrating a broad spectrum of biological processes, either by covalently modifying …
Human phospho‐signaling networks of SARS‐CoV‐2 infection are rewired by population genetic variants
SARS‐CoV‐2 infection hijacks signaling pathways and induces protein–protein interactions
between human and viral proteins. Human genetic variation may impact SARS‐CoV‐2 …
between human and viral proteins. Human genetic variation may impact SARS‐CoV‐2 …
Germline genetic biomarkers to stratify patients for personalized radiation treatment
I Deichaite, A Hopper, L Krockenberger… - Journal of translational …, 2022 - Springer
Background Precision medicine incorporating genetic profiling is becoming a standard of
care in medical oncology. However, in the field of radiation oncology there is limited use of …
care in medical oncology. However, in the field of radiation oncology there is limited use of …
From 'omics to multi-omics technologies: the discovery of novel causal mediators
Abstract Purpose of Review 'Omics studies provide a comprehensive characterisation of a
biological entity, such as the genome, epigenome, transcriptome, proteome, metabolome, or …
biological entity, such as the genome, epigenome, transcriptome, proteome, metabolome, or …
Functional analysis of the stable phosphoproteome reveals cancer vulnerabilities
Motivation The advance of mass spectrometry-based technologies enabled the profiling of
the phosphoproteomes of a multitude of cell and tissue types. However, current research …
the phosphoproteomes of a multitude of cell and tissue types. However, current research …
Comprehensive in silico prioritization of pathogenic nsSNPs in human β-adducin gene towards finding its relation with cancer
AM Goswami - Human Gene, 2022 - Elsevier
The adducin family consists of three closely related proteins ADD1 (α-isoform), ADD2 (β-
isoform) and ADD3 (γ-isoform) with similar domain structures. Adducins exist as …
isoform) and ADD3 (γ-isoform) with similar domain structures. Adducins exist as …