[HTML][HTML] COVID-19 and the chemical senses: supporting players take center stage
The main neurological manifestation of COVID-19 is loss of smell or taste. The high
incidence of smell loss without significant rhinorrhea or nasal congestion suggests that …
incidence of smell loss without significant rhinorrhea or nasal congestion suggests that …
Interaction of SARS-CoV-2 and other coronavirus with ACE (angiotensin-converting enzyme)-2 as their main receptor: therapeutic implications
AM Davidson, J Wysocki, D Batlle - Hypertension, 2020 - Am Heart Assoc
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 originated from Wuhan,
China, in December 2019 and rapidly spread to other areas worldwide. Since then …
China, in December 2019 and rapidly spread to other areas worldwide. Since then …
[HTML][HTML] β-Coronaviruses use lysosomes for egress instead of the biosynthetic secretory pathway
S Ghosh, TA Dellibovi-Ragheb, A Kerviel, E Pak, Q Qiu… - Cell, 2020 - cell.com
Summary β-Coronaviruses are a family of positive-strand enveloped RNA viruses that
includes the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Much is …
includes the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Much is …
A single-cell atlas of the human healthy airways
M Deprez, LE Zaragosi, M Truchi… - American journal of …, 2020 - atsjournals.org
Rationale: The respiratory tract constitutes an elaborate line of defense that is based on a
unique cellular ecosystem. Objectives: We aimed to investigate cell population distributions …
unique cellular ecosystem. Objectives: We aimed to investigate cell population distributions …
Extracellular vimentin is an attachment factor that facilitates SARS-CoV-2 entry into human endothelial cells
SARS-CoV-2 entry into host cells is a crucial step for virus tropism, transmission, and
pathogenesis. Angiotensin-converting enzyme 2 (ACE2) has been identified as the primary …
pathogenesis. Angiotensin-converting enzyme 2 (ACE2) has been identified as the primary …
Hypertension, a moving target in COVID-19: current views and perspectives
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) associates with a considerable high rate of mortality and …
coronavirus 2 (SARS-CoV-2) associates with a considerable high rate of mortality and …
Anosmia in COVID-19: mechanisms and significance
The global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) remains a challenge for prevention due …
respiratory syndrome coronavirus 2 (SARS-CoV-2) remains a challenge for prevention due …
The key role of Warburg effect in SARS-CoV-2 replication and associated inflammatory response
P Icard, H Lincet, Z Wu, A Coquerel, P Forgez… - Biochimie, 2021 - Elsevier
Current mortality due to the Covid-19 pandemic (approximately 1.2 million by November
2020) demonstrates the lack of an effective treatment. As replication of many viruses …
2020) demonstrates the lack of an effective treatment. As replication of many viruses …
The surviving sepsis campaign: research priorities for coronavirus disease 2019 in critical illness
CM Coopersmith, M Antonelli, SR Bauer… - Critical care …, 2021 - journals.lww.com
OBJECTIVES: To identify research priorities in the management, pathophysiology, and host
response of coronavirus disease 2019 in critically ill patients. DESIGN: The Surviving Sepsis …
response of coronavirus disease 2019 in critically ill patients. DESIGN: The Surviving Sepsis …
SARS-CoV-2 and SARS-CoV spike-mediated cell-cell fusion differ in their requirements for receptor expression and proteolytic activation
BF Hörnich, AK Großkopf, S Schlagowski… - Journal of …, 2021 - Am Soc Microbiol
Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) infects cells
through interaction of its spike protein (SARS2-S) with angiotensin-converting enzyme 2 …
through interaction of its spike protein (SARS2-S) with angiotensin-converting enzyme 2 …