The role of insect cytochrome P450s in mediating insecticide resistance

M Ye, B Nayak, L Xiong, C Xie, Y Dong, M You, Z Yuchi… - Agriculture, 2022 - mdpi.com
In many organisms, cytochrome P450 enzymes are the primary detoxifying enzymes.
Enhanced P450 activity can be mediated by the emergence of new genes, increased …

Recent advances of mitochondrial complex I inhibitors for cancer therapy: Current status and future perspectives

Y Zhou, J Zou, J Xu, Y Zhou, X Cen, Y Zhao - European Journal of …, 2023 - Elsevier
Mitochondrial complex I (CI) as a critical multifunctional respiratory complex of electron
transport chain (ETC) in mitochondrial oxidative phosphorylation has been identified as vital …

Effect of nanostructure lipid carrier of methylene blue and monoterpenes as enzymes inhibitor for Culex pipiens

IT Radwan, MZ Sayed-Ahmed, NAR Ghazawy… - Scientific Reports, 2023 - nature.com
Solid lipid nanoparticles second generation, nanostructure lipid carrier (NLC), is one of the
most important biodegradable nanoparticles. Nanostructure Lipid carrier (NLC) was used to …

Molecular drivers of insecticide resistance in the Sahelo-Sudanian populations of a major malaria vector Anopheles coluzzii

SS Ibrahim, A Muhammad, J Hearn, GD Weedall… - BMC biology, 2023 - Springer
Background Information on common markers of metabolic resistance in malaria vectors from
countries sharing similar eco-climatic characteristics can facilitate coordination of malaria …

Review and meta-analysis of the evidence for choosing between specific pyrethroids for programmatic purposes

N Lissenden, MD Kont, J Essandoh, HM Ismail… - Insects, 2021 - mdpi.com
Simple Summary A group of insecticides, called pyrethroids, are the main strategy for
controlling the mosquito vectors of malaria. Pyrethroids are used in all insecticide-treated …

Sympatric Populations of the Anopheles gambiae Complex in Southwest Burkina Faso Evolve Multiple Diverse Resistance Mechanisms in Response to Intense …

J Williams, VA Ingham, M Morris, KH Toé, AS Hien… - Insects, 2022 - mdpi.com
Simple Summary Targeting mosquitoes with insecticides is one of the most effective
methods to prevent malaria transmission. Although numbers of malaria cases have declined …

Multi‐omics analysis identifies a CYP9K1 haplotype conferring pyrethroid resistance in the malaria vector Anopheles funestus in East Africa

J Hearn, CS Djoko Tagne, SS Ibrahim… - Molecular …, 2022 - Wiley Online Library
Metabolic resistance to pyrethroids is a menace to the continued effectiveness of malaria
vector controls. Its molecular basis is complex and varies geographically across Africa. Here …

Strain characterisation for measuring bioefficacy of ITNs treated with two active ingredients (Dual-AI ITNs): developing a robust protocol by building consensus

RS Lees, JS Armistead, S Azizi, E Constant… - Insects, 2022 - mdpi.com
Simple Summary New types of bed nets are being developed which contain a pyrethroid
plus a second chemical because of the development and increased frequency of mosquito …

Automated phenotyping of mosquito larvae enables high-throughput screening for novel larvicides and offers potential for smartphone-based detection of larval …

SD Buckingham, FA Partridge, BC Poulton… - PLoS neglected …, 2021 - journals.plos.org
Pyrethroid-impregnated nets have contributed significantly to halving the burden of malaria
but resistance threatens their future efficacy and the pipeline of new insecticides is short …

Effects of tolfenpyrad exposure on development and response mechanism in the silkworm, Bombyx mori

Q Wang, Z Sun, Z Huang, S Ma, K Chen, X Ju - Pesticide Biochemistry and …, 2023 - Elsevier
Tolfenpyrad is a broad spectrum of insecticide that can effectively kill different types of pests,
including Lepidoptera. However, due to improper use, the adverse effects of tolfenpyrad on …