Memory engrams: Recalling the past and imagining the future

SA Josselyn, S Tonegawa - Science, 2020 - science.org
BACKGROUND The idea that memory is stored as enduring changes in the brain dates
back at least to the time of Plato and Aristotle (circa 350 BCE), but its scientific articulation …

Fear memory

I Izquierdo, CRG Furini, JC Myskiw - Physiological reviews, 2016 - journals.physiology.org
Fear memory is the best-studied form of memory. It was thoroughly investigated in the past
60 years mostly using two classical conditioning procedures (contextual fear conditioning …

[HTML][HTML] Molecular mechanisms of fear learning and memory

JP Johansen, CK Cain, LE Ostroff, JE LeDoux - Cell, 2011 - cell.com
Pavlovian fear conditioning is a particularly useful behavioral paradigm for exploring the
molecular mechanisms of learning and memory because a well-defined response to a …

Chemogenetic tools to interrogate brain functions

SM Sternson, BL Roth - Annual review of neuroscience, 2014 - annualreviews.org
Elucidating the roles of neuronal cell types for physiology and behavior is essential for
understanding brain functions. Perturbation of neuron electrical activity can be used to probe …

Plastic synaptic networks of the amygdala for the acquisition, expression, and extinction of conditioned fear

HC Pape, D Pare - Physiological reviews, 2010 - journals.physiology.org
The last 10 years have witnessed a surge of interest for the mechanisms underlying the
acquisition and extinction of classically conditioned fear responses. In part, this results from …

[图书][B] Cognitive psychology: Connecting mind, research and everyday experience

EB Goldstein - 2015 - teachpsych.org
Cognitive psychology is the scientific study of mental processes such as attention, memory,
language, decision-making, and intelligence. Students examine major discipline-related …

The organization of recent and remote memories

PW Frankland, B Bontempi - Nature reviews neuroscience, 2005 - nature.com
A fundamental question in memory research is how our brains can form enduring memories.
In humans, memories of everyday life depend initially on the medial temporal lobe system …

The neurobiology of consolidations, or, how stable is the engram?

Y Dudai - Annu. Rev. Psychol., 2004 - annualreviews.org
Consolidation is the progressive postacquisition stabilization of long-term memory. The term
is commonly used to refer to two types of processes: synaptic consolidation, which is …

Psychobiological mechanisms of resilience and vulnerability: implications for successful adaptation to extreme stress

DS Charney - American journal of Psychiatry, 2004 - Am Psychiatric Assoc
OBJECTIVE: Most research on the effects of severe psychological stress has focused on
stress-related psychopathology. Here, the author develops psychobiological models of …

Stress, depression, and neuroplasticity: a convergence of mechanisms

C Pittenger, RS Duman - Neuropsychopharmacology, 2008 - nature.com
Increasing evidence demonstrates that neuroplasticity, a fundamental mechanism of
neuronal adaptation, is disrupted in mood disorders and in animal models of stress. Here we …