Urogenital tuberculosis—epidemiology, pathogenesis and clinical features
A Muneer, B Macrae, S Krishnamoorthy… - Nature Reviews …, 2019 - nature.com
Tuberculosis (TB) is the most common cause of death from infectious disease worldwide. A
substantial proportion of patients presenting with extrapulmonary TB have urogenital TB (UG …
substantial proportion of patients presenting with extrapulmonary TB have urogenital TB (UG …
Biomarkers and diagnostics for tuberculosis: progress, needs, and translation into practice
Human infection with Mycobacterium tuberculosis can progress to active disease, be
contained as latent infection, or be eradicated by the host response. Tuberculosis …
contained as latent infection, or be eradicated by the host response. Tuberculosis …
CRISPR detection of circulating cell-free Mycobacterium tuberculosis DNA in adults and children, including children with HIV: a molecular diagnostics study
Background Tuberculosis remains a leading cause of global mortality, especially for adults
and children living with HIV (CLHIV) underdiagnosed by sputum-based assays. Non-sputum …
and children living with HIV (CLHIV) underdiagnosed by sputum-based assays. Non-sputum …
Update on tuberculosis biomarkers: from correlates of risk, to correlates of active disease and of cure from disease
D Goletti, MR Lee, JY Wang, N Walter… - …, 2018 - Wiley Online Library
Tuberculosis (TB) remains a devastating disease, yet despite its enormous toll on global
health, tools to control TB are insufficient and often outdated. TB Biomarkers (TB‐BM) would …
health, tools to control TB are insufficient and often outdated. TB Biomarkers (TB‐BM) would …
Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities
R McNerney, M Maeurer, I Abubakar… - Journal of Infectious …, 2012 - academic.oup.com
Tuberculosis is unique among the major infectious diseases in that it lacks accurate rapid
point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to …
point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to …
Diagnosis of extrapulmonary tuberculosis by PCR
During the last two decades, the resurgence of tuberculosis (TB) has been documented in
both developed and developing nations, and much of this increase in TB burden coincided …
both developed and developing nations, and much of this increase in TB burden coincided …
TBscreen: A passive cough classifier for tuberculosis screening with a controlled dataset
Recent respiratory disease screening studies suggest promising performance of cough
classifiers, but potential biases in model training and dataset quality preclude robust …
classifiers, but potential biases in model training and dataset quality preclude robust …
New specimens and laboratory diagnostics for childhood pulmonary TB: progress and prospects
Childhood pulmonary TB (PTB) is under diagnosed, in part due to difficulties in obtaining
microbiological confirmation. However, given the poor specificity of clinical diagnosis …
microbiological confirmation. However, given the poor specificity of clinical diagnosis …
Genome-wide tiled detection of circulating Mycobacterium tuberculosis cell-free DNA using Cas13
SG Thakku, J Lirette, K Murugesan, J Chen… - Nature …, 2023 - nature.com
Detection of microbial cell-free DNA (cfDNA) circulating in the bloodstream has emerged as
a promising new approach for diagnosing infection. Microbial diagnostics based on cfDNA …
a promising new approach for diagnosing infection. Microbial diagnostics based on cfDNA …
[HTML][HTML] Diagnosing infections—current and anticipated technologies for point-of-care diagnostics and home-based testing
L Bissonnette, MG Bergeron - Clinical Microbiology and Infection, 2010 - Elsevier
In recent years, we have witnessed many transitions in healthcare systems around the
globe. For example, population expansion and ageing, and the human immunodeficiency …
globe. For example, population expansion and ageing, and the human immunodeficiency …