Metal complexes of a 5-nitro-8-hydroxyquinoline-proline hybrid with enhanced water solubility targeting multidrug resistant cancer cells

T Pivarcsik, V Pósa, H Kovács, NV May… - International Journal of …, 2022 - mdpi.com
Multidrug resistance (MDR) in cancer is one of the major obstacles of chemotherapy. We
have recently identified a series of 8-hydroxyquinoline Mannich base derivatives with MDR …

Half sandwich-type osmium, ruthenium, iridium and rhodium complexes with bidentate glycosyl heterocyclic ligands induce cytostasis in platinum-resistant ovarian …

I Kacsir, A Sipos, T Kiss, E Major, N Bajusz… - Frontiers in …, 2023 - frontiersin.org
The toxicity of and resistance to platinum complexes as cisplatin, oxaliplatin or carboplatin
calls for the replacement of these therapeutic agents in clinical settings. We have previously …

Half-Sandwich Type Platinum-Group Metal Complexes of C-Glucosaminyl Azines: Synthesis and Antineoplastic and Antimicrobial Activities

I Kacsir, A Sipos, E Major, N Bajusz, A Bényei… - Molecules, 2023 - mdpi.com
While platinum-based compounds such as cisplatin form the backbone of chemotherapy, the
use of these compounds is limited by resistance and toxicity, driving the development of …

Therapeutic Potential of Rhodium Complexes

A Hussain, MF Alajmi, MA Lone, WA Wani - Therapeutic Rhodium …, 2023 - Springer
Until recently, rhodium was one of the neglected metals towards drug development.
However, research in the recent past witnessed the development of several rhodium …

C-és N-Glikopiranozil-heterociklusok platinafém félszendvics komplexeinek előállítása biológiai alkalmazásokra

I Kacsir - 2024 - dea.lib.unideb.hu
Kutatómunkám során új típusú platinafém félszendvics komplexek előállítását valósítottam
meg, melyekbe N, N-kelátképző ligandumokként öt-és hattagú C-és N-glikopiranozil …

[PDF][PDF] Journal of Molecular and Pharmaceutical Sciences

B Imenea, MS Eddineb, MM Akramb, B Malikac… - J. Mol. Pharm …, 2023 - asjp.cerist.dz
Genotoxic property of four new antibacterial sulfonamides 1a-d has been evaluated in this
study using two standard genotoxicity assays: the Salmonella typhimurium mutagenicity …