Melatonin, an indoleamine hormone produced and secreted at night by pinealocytes and
extra-pineal cells, plays an important role in timing circadian rhythms (24-h internal clock) …

Osteoarthritis (OA) is a degenerative joint disease characterized by progressive erosion of
articular cartilage. As chondrocytes are the only cell type forming the articular cartilage, their …

The pineal hormone melatonin has attracted great scientific interest since its discovery in
1958. Despite the enormous number of basic and clinical studies the exact role of melatonin …

Melatonin has a wide variety of beneficial actions at the level of the gonads and their
adnexa. Some actions are mediated via its classic membrane melatonin receptors while …

While melatonin was once thought of simply as a sleep-inducing hormone, recent research
has resulted in development of a deeper understanding of the complex physiological activity …

Melatonin, an indolamine mainly released from the pineal gland, is associated with many
biological functions, namely, the modulation of circadian and seasonal rhythms, sleep …

There is growing concern that some cytotoxic regimens for cancer adversely affect
spermatogenesis and male fertility. Increasing evidence demonstrated that melatonin has …

Melatonin has antitumor activity via several mechanisms including its antiproliferative and
pro‐apoptotic effects as well as its potent antioxidant actions, although recent evidence has …

Infertility is an increasing global public health concern with socio-psychological implications
for affected couples. Remarkable advances in reproductive medicine have led to successful …

Introduction: Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease associated
with disruption of alveolar epithelial cell layer and expansion of fibroblasts/myofibroblasts …