Wound healing: cellular mechanisms and pathological outcomes

HN Wilkinson, MJ Hardman - Open biology, 2020 - royalsocietypublishing.org
Wound healing is a complex, dynamic process supported by a myriad of cellular events that
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …

Skin applications of cannabidiol: sources, effects, delivery systems, marketed formulations and safety

BP Ferreira, G Costa, F Mascarenhas-Melo… - Phytochemistry …, 2023 - Springer
In recent decades, the therapeutic potential of cannabinoids and analogous compounds has
been intensively investigated. The endocannabinoid system has already been identified in …

Layer-by-layer microneedle-mediated rhEGF transdermal delivery for enhanced wound epidermal regeneration and angiogenesis

R Yuan, N Yang, Y Huang, W Li, Y Zeng… - … Applied Materials & …, 2023 - ACS Publications
Appropriate treatments for acute traumas tend to avoid hemorrhages, vascular damage, and
infections. However, in the homeostasis-imbalanced wound microenvironment, currently …

A robotic venous leg ulcer system reveals the benefits of negative pressure wound therapy in effective fluid handling

A Orlov, M Ciliberti, R Somma… - International Wound …, 2024 - Wiley Online Library
We applied a market‐leading, single‐use negative pressure wound therapy device to a
robotic venous leg ulcer system and compared its fluid handling performance with that of …

Carboxymethyl Chitosan Hydrogels for Effective Wound Healing—An Animal Study

KK Kłosiński, RA Wach, W Kruczkowska… - Journal of Functional …, 2023 - mdpi.com
Hydrogels have various applications in medicine, for example, in systems for controlled drug
release or as wound dressings, where they provide an appropriate environment for healing …

Molecular mechanisms of action of negative pressure wound therapy: a systematic review

B Ravindhran, N Schafer, A Howitt… - Expert Reviews in …, 2023 - cambridge.org
Negative pressure wound therapy (NPWT) has significantly advanced wound care and
continues to find new applications. Its effects at a molecular level however, remain a subject …

Incisional negative pressure wound therapy after revascularisation surgery in patients with peripheral arterial disease: a randomised trial (PICO-Vasc Study)

LR Lorenzo, EA Salto, EG Cañas, ZM González… - European Journal of …, 2024 - Elsevier
Objective This study assessed the potential benefits of using incisional negative pressure
wound therapy (iNPWT) for patients undergoing revascularisation due to peripheral arterial …

Novel cell culture system for monitoring cells during continuous and variable negative‐pressure wound therapy

T Yamashiro, T Kushibiki, Y Mayumi… - Skin Research and …, 2023 - Wiley Online Library
Background Although the clinical efficacy of negative‐pressure wound therapy (NPWT) is
well known, many of its molecular biological mechanisms remain unresolved, mainly due to …

A prospective, randomized, controlled clinical study on the effectiveness of a single‐use negative pressure wound therapy system, compared to traditional negative …

RS Kirsner, D Zimnitsky… - Wound Repair and …, 2021 - Wiley Online Library
Abstract A multicenter, phase 4, randomized, comparative‐efficacy study in subjects with
lower extremity wounds was carried out to compare wound closure rates, for a single‐use …