Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets
The arachidonic acid (AA) pathway plays a key role in cardiovascular biology,
carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc. Esterified …
carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc. Esterified …
The biosynthesis of enzymatically oxidized lipids
AA Hajeyah, WJ Griffiths, Y Wang, AJ Finch… - Frontiers in …, 2020 - frontiersin.org
Enzymatically oxidized lipids are a specific group of biomolecules that function as key
signaling mediators and hormones, regulating various cellular and physiological processes …
signaling mediators and hormones, regulating various cellular and physiological processes …
Lipoxygenase and leukotriene pathways: biochemistry, biology, and roles in disease
JZ Haeggstrom, CD Funk - Chemical reviews, 2011 - ACS Publications
Metabolism of arachidonic acid leads to several families of lipid mediators, including
prostaglandins, thromboxane, leukotrienes, and lipoxins, along two major metabolic …
prostaglandins, thromboxane, leukotrienes, and lipoxins, along two major metabolic …
Thematic Review Series: proteomics. An integrated omics analysis of eicosanoid biology1 [S]
MW Buczynski, DS Dumlao, EA Dennis - Journal of lipid research, 2009 - ASBMB
Eicosanoids have been implicated in a vast number of devastating inflammatory conditions,
including arthritis, atherosclerosis, pain, and cancer. Currently, over a hundred different …
including arthritis, atherosclerosis, pain, and cancer. Currently, over a hundred different …
[图书][B] Principles of enzymology for the food sciences
JR Whitaker - 2018 - taylorfrancis.com
This second edition explains the fundamentals of enzymology and describes the role of
enzymes in food, agricultural and health sciences. Among other topics, it provides new …
enzymes in food, agricultural and health sciences. Among other topics, it provides new …
The eicosanoids and their biochemical mechanisms of action.
WL Smith - Biochemical Journal, 1989 - ncbi.nlm.nih.gov
Introduction Low dosages of aspirin [1, 2] and ingestion of certain fish oils [3-6] have recently
been touted as having some value in preventing cardiovascular disease. Aspirin is a …
been touted as having some value in preventing cardiovascular disease. Aspirin is a …
Neural organization for the long-term memory of paired associates
K Sakai, Y Miyashita - Nature, 1991 - nature.com
MOST of our long-term memories of episodes or objects are organized so that we can
retrieve them by association. Clinical neuropsychologists assess human memory by the …
retrieve them by association. Clinical neuropsychologists assess human memory by the …
Structural and functional biology of arachidonic acid 15-lipoxygenase-1 (ALOX15)
I Ivanov, H Kuhn, D Heydeck - Gene, 2015 - Elsevier
Lipoxygenases (LOX) form a family of lipid peroxidizing enzymes, which have been
implicated in a number of physiological processes and in the pathogenesis of inflammatory …
implicated in a number of physiological processes and in the pathogenesis of inflammatory …
The role of leukotrienes in inflammation
WR Henderson - Annals of internal medicine, 1994 - acpjournals.org
Objective: To review the biochemistry and biological activities of leukotrienes, focusing on
their role in the mediation of inflammatory diseases. Data Sources: MEDLINE (1966-1994) …
their role in the mediation of inflammatory diseases. Data Sources: MEDLINE (1966-1994) …
Discovery of a second 15S-lipoxygenase in humans
AR Brash, WE Boeglin… - Proceedings of the …, 1997 - National Acad Sciences
The lipoxygenase metabolism of arachidonic acid occurs in specific blood cell types and
epithelial tissues and is activated in inflammation and tissue injury. In the course of studying …
epithelial tissues and is activated in inflammation and tissue injury. In the course of studying …