Calmodulin (CaM) is a ubiquitous Ca 2+ receptor protein mediating a large number of
signaling processes in all eukaryotic cells. CaM plays a central role in regulating a myriad of …

The transient receptor potential melastatin-subfamily member 7 (TRPM7) is a ubiquitously
expressed chanzyme that possesses an ion channel permeable to the divalent cations …

The study of calcium channels in molecular mechanisms of cancer transformation is still a
novel area of research. Several studies, mostly conducted on cancer cell lines, however …

Aberrant increase in the expression levels of sarco/endoplasmic reticulum calcium ATPase
(SERCA), which regulates Ca 2+ homeostasis, has been observed in ovarian cancers. In …

Calcium homeostasis plays an essential role in maintaining excitation–contraction coupling
(ECC) in cardiomyocytes, including calcium release, recapture, and storage. Disruption of …

Calcium (Ca2+) signals initiate egg activation across the animal kingdom and in at least
some plants. These signals are crucial for the success of development and, in the case of …

Electromagnetic field (EMF) exposures affect many biological systems. The reproducibility of
these effects is related to the intensity, duration, frequency, and pattern of the EMF. We have …

Englerin A is a structurally unique natural product reported to selectively inhibit growth of
renal cell carcinoma cell lines. A large scale phenotypic cell profiling experiment (CLiP) of …

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and typically fatal lung disease
with a very low survival rate. Excess accumulation of fibroblasts, myofibroblasts and …

Abstract Intracellular calcium (Ca 2+) is an essential second messenger in eukaryotic cells
regulating numerous cellular functions such as contraction, secretion, immunity, growth, and …