[HTML][HTML] Neutrophil extracellular traps in systemic autoimmune and autoinflammatory diseases
G Wigerblad, MJ Kaplan - Nature Reviews Immunology, 2023 - nature.com
Systemic autoimmune diseases are characterized by the failure of the immune system to
differentiate self from non-self. These conditions are associated with significant morbidity …
differentiate self from non-self. These conditions are associated with significant morbidity …
[HTML][HTML] Immune response in COVID-19: what is next?
Abstract The coronavirus disease 2019 (COVID-19) has been a global pandemic for more
than 2 years and it still impacts our daily lifestyle and quality in unprecedented ways. A …
than 2 years and it still impacts our daily lifestyle and quality in unprecedented ways. A …
[HTML][HTML] Patients with COVID-19: in the dark-NETs of neutrophils
SARS-CoV-2 infection poses a major threat to the lungs and multiple other organs,
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …
[HTML][HTML] From purines to purinergic signalling: molecular functions and human diseases
Purines and their derivatives, most notably adenosine and ATP, are the key molecules
controlling intracellular energy homoeostasis and nucleotide synthesis. Besides, these …
controlling intracellular energy homoeostasis and nucleotide synthesis. Besides, these …
NETworking with cancer: The bidirectional interplay between cancer and neutrophil extracellular traps
JM Adrover, SAC McDowell, XY He, DF Quail… - Cancer Cell, 2023 - cell.com
Neutrophils are major effectors and regulators of the immune system. They play critical roles
not only in the eradication of pathogens but also in cancer initiation and progression …
not only in the eradication of pathogens but also in cancer initiation and progression …
[HTML][HTML] NETosis: molecular mechanisms, role in physiology and pathology
NV Vorobjeva, BV Chernyak - Biochemistry (Moscow), 2020 - Springer
NETosis is a program for formation of neutrophil extracellular traps (NETs), which consist of
modified chromatin decorated with bactericidal proteins from granules and cytoplasm …
modified chromatin decorated with bactericidal proteins from granules and cytoplasm …
[HTML][HTML] Vascular occlusion by neutrophil extracellular traps in COVID-19
M Leppkes, J Knopf, E Naschberger, A Lindemann… - …, 2020 - thelancet.com
Background Coronavirus induced disease 2019 (COVID-19) can be complicated by severe
organ damage leading to dysfunction of the lungs and other organs. The processes that …
organ damage leading to dysfunction of the lungs and other organs. The processes that …
[HTML][HTML] A review of neutrophil extracellular traps (NETs) in disease: potential anti-NETs therapeutics
V Mutua, LJ Gershwin - Clinical reviews in allergy & immunology, 2021 - Springer
Activated neutrophils release neutrophil extracellular traps (NETs) in response to a variety of
stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of …
stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of …
Neutrophil extracellular traps: from physiology to pathology
At the frontline of the host defence response, neutrophil antimicrobial functions have
adapted to combat infections and injuries of different origins and magnitude. The release of …
adapted to combat infections and injuries of different origins and magnitude. The release of …
The tumor microenvironment innately modulates cancer progression
DC Hinshaw, LA Shevde - Cancer research, 2019 - AACR
Cancer development and progression occurs in concert with alterations in the surrounding
stroma. Cancer cells can functionally sculpt their microenvironment through the secretion of …
stroma. Cancer cells can functionally sculpt their microenvironment through the secretion of …