Free radical properties, source and targets, antioxidant consumption and health

G Martemucci, C Costagliola, M Mariano, L D'andrea… - Oxygen, 2022 - mdpi.com
Free radicals have acquired growing importance in the fields of biology and medicine. They
are produced during many different endogenous and exogenous processes. Mitochondria …

Functions of ROS in macrophages and antimicrobial immunity

M Herb, M Schramm - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are a chemically defined group of reactive molecules
derived from molecular oxygen. ROS are involved in a plethora of processes in cells in all …

ROS homeostasis in abiotic stress tolerance in plants

KK Nadarajah - International journal of molecular sciences, 2020 - mdpi.com
Climate change-induced abiotic stress results in crop yield and production losses. These
stresses result in changes at the physiological and molecular level that affect the …

Persister cancer cells: Iron addiction and vulnerability to ferroptosis

R Rodriguez, SL Schreiber, M Conrad - Molecular cell, 2022 - cell.com
Ferroptosis is a unique type of non-apoptotic cell death resulting from the unrestrained
occurrence of peroxidized phospholipids, which are subject to iron-mediated production of …

Reactive oxygen species in metabolic and inflammatory signaling

SJ Forrester, DS Kikuchi, MS Hernandes, Q Xu… - Circulation …, 2018 - Am Heart Assoc
Reactive oxygen species (ROS) are well known for their role in mediating both physiological
and pathophysiological signal transduction. Enzymes and subcellular compartments that …

The impact of oxidative stress in human pathology: Focus on gastrointestinal disorders

R Vona, L Pallotta, M Cappelletti, C Severi… - Antioxidants, 2021 - mdpi.com
Accumulating evidence shows that oxidative stress plays an essential role in the
pathogenesis and progression of many diseases. The imbalance between the production of …

Superoxide dismutases: Dual roles in controlling ROS damage and regulating ROS signaling

Y Wang, R Branicky, A Noë, S Hekimi - Journal of Cell Biology, 2018 - rupress.org
Superoxide dismutases (SODs) are universal enzymes of organisms that live in the
presence of oxygen. They catalyze the conversion of superoxide into oxygen and hydrogen …

Reactive oxygen species and cancer paradox: to promote or to suppress?

S Galadari, A Rahman, S Pallichankandy… - Free Radical Biology …, 2017 - Elsevier
Reactive oxygen species (ROS), a group of highly reactive ions and molecules, are
increasingly being appreciated as powerful signaling molecules involved in the regulation of …

Pathomechanisms of oxidative stress in inflammatory bowel disease and potential antioxidant therapies

T Tian, Z Wang, J Zhang - Oxidative medicine and cellular …, 2017 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic gastrointestinal disease whose incidence has
risen worldwide in recent years. Accumulating evidence shows that oxidative stress plays an …

[HTML][HTML] The role of oxidative stress in neurodegenerative diseases

GH Kim, JE Kim, SJ Rhie, S Yoon - Experimental neurobiology, 2015 - ncbi.nlm.nih.gov
Oxidative stress is induced by an imbalanced redox states, involving either excessive
generation of reactive oxygen species (ROS) or dysfunction of the antioxidant system. The …