Regulation of Cation Balance in Saccharomyces cerevisiae
MS Cyert, CC Philpott - Genetics, 2013 - academic.oup.com
All living organisms require nutrient minerals for growth and have developed mechanisms to
acquire, utilize, and store nutrient minerals effectively. In the aqueous cellular environment …
acquire, utilize, and store nutrient minerals effectively. In the aqueous cellular environment …
The oxidative stress of zinc deficiency
DJ Eide - Metallomics, 2011 - academic.oup.com
Zinc is an essential catalytic and structural cofactor for many enzymes and other proteins.
While Zn2+ is not redox active under physiological conditions, it has been known for many …
While Zn2+ is not redox active under physiological conditions, it has been known for many …
[HTML][HTML] Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors
P Kemmeren, K Sameith, LAL Van De Pasch… - Cell, 2014 - cell.com
To understand regulatory systems, it would be useful to uniformly determine how different
components contribute to the expression of all other genes. We therefore monitored mRNA …
components contribute to the expression of all other genes. We therefore monitored mRNA …
Application of transcriptome analysis: Oxidative stress, inflammation and microtubule activity disorder caused by ammonia exposure may be the primary factors of …
S Wang, X Li, W Wang, H Zhang, S Xu - Science of the Total Environment, 2019 - Elsevier
Abstract Ammonia (NH 3), an inhaled harmful gas, is not only an important volatile in
fertilizer production and ranching, but also the main basic component of haze. However, the …
fertilizer production and ranching, but also the main basic component of haze. However, the …
The cellular economy of the Saccharomyces cerevisiae zinc proteome
Y Wang, E Weisenhorn, CW MacDiarmid… - Metallomics, 2018 - academic.oup.com
Zinc is an essential cofactor for many proteins. A key mechanism of zinc homeostasis during
deficiency is “zinc sparing” in which specific zinc-binding proteins are repressed to reduce …
deficiency is “zinc sparing” in which specific zinc-binding proteins are repressed to reduce …
[HTML][HTML] Fungal zinc metabolism and its connections to virulence
CC Staats, L Kmetzsch, A Schrank… - Frontiers in cellular and …, 2013 - frontiersin.org
Zinc is a ubiquitous metal in all life forms, as it is a structural component of the almost 10% of
eukaryotic proteins, which are called zinc-binding proteins. In zinc-limiting conditions such …
eukaryotic proteins, which are called zinc-binding proteins. In zinc-limiting conditions such …
Zinc'ing sensibly: controlling zinc homeostasis at the transcriptional level
Zinc-responsive transcription factors are found in all kingdoms of life and include the
transcriptional activators ZntR, SczA, Zap1, bZip19, bZip23, and MTF-1, and transcriptional …
transcriptional activators ZntR, SczA, Zap1, bZip19, bZip23, and MTF-1, and transcriptional …
[HTML][HTML] Zinc limitation triggers anticipatory adaptations in Mycobacterium tuberculosis
A Dow, P Sule, TJ O'Donnell, A Burger… - PLoS …, 2021 - journals.plos.org
Mycobacterium tuberculosis (Mtb) has complex and dynamic interactions with the human
host, and subpopulations of Mtb that emerge during infection can influence disease …
host, and subpopulations of Mtb that emerge during infection can influence disease …
[HTML][HTML] Zap1 Regulates Zinc Homeostasis and Modulates Virulence in Cryptococcus gattii
RO Schneider, NSS Fogaça, L Kmetzsch, A Schrank… - 2012 - journals.plos.org
Zinc homeostasis is essential for fungal growth, as this metal is a critical structural
component of several proteins, including transcription factors. The fungal pathogen …
component of several proteins, including transcription factors. The fungal pathogen …
[HTML][HTML] Involvement of Sulfur in the Biosynthesis of Essential Metabolites in Pathogenic Fungi of Animals, Particularly Aspergillus spp.: Molecular and Therapeutic …
AM Traynor, KJ Sheridan, GW Jones… - Frontiers in …, 2019 - frontiersin.org
Fungal sulfur uptake is required for incorporation into the sidechains of the amino acids
cysteine and methionine, and is also essential for the biosynthesis of the antioxidant …
cysteine and methionine, and is also essential for the biosynthesis of the antioxidant …