Simple Summary The high lethality of colorectal cancer (CRC) is anticipated to continue in
the following decades. Early-stage CRC is entirely treatable with surgery and adjuvant …

Colorectal cancer (CRC) is highly heterogeneous at the genetic and molecular level, which
has major repercussions on the efficacy of immunotherapy. A small subset of CRCs exhibit …

Immune checkpoint inhibitors targeting programmed cell death protein 1, programmed death-
ligand 1, and cytotoxic T-lymphocyte-associated protein 4 provide deep and durable …

Cancer immunotherapy attempts to harness the power and specificity of the immune system
to treat tumours. The molecular identification of human cancer-specific antigens has allowed …

Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune
responses according to peripheral cues. After four decades of research, we now know that …

A biomaterial-based vaccination system that uses minimal extracorporeal manipulation
could provide in situ enhancement of dendritic cell (DC) numbers, a physical space where …

Great progress has been made in the field of tumor immunology in the past decade, but
optimism about the clinical application of currently available cancer vaccine approaches is …

Simple Summary Cancer immunotherapy is currently focused mainly on the enhancement of
the effector function of T cells. However, dendritic cells (DCs) are needed to prime T cells …

Dendritic cells take up antigens in peripheral tissues, process them into proteolytic peptides,
and load these peptides onto major histocompatibility complex (MHC) class I and II …

Engineering natural macrophage cell membrane-camouflaged mesoporous silica
nanocapsules can reduce the arrested percentage of immune cells and tissues, effectively …