The Sonogashira reaction: a booming methodology in synthetic organic chemistry

R Chinchilla, C Nájera - Chemical reviews, 2007 - ACS Publications
The array of transition-metal-catalyzed cross-coupling reactions can easily be considered
nowadays cornerstones in the field of organic synthesis. 1, 2 Among them, the palladium …

Controlled microwave heating in modern organic synthesis

CO Kappe - Angewandte Chemie International Edition, 2004 - Wiley Online Library
Although fire is now rarely used in synthetic chemistry, it was not until Robert Bunsen
invented the burner in 1855 that the energy from this heat source could be applied to a …

Palladium‐catalyzed coupling reactions of aryl chlorides

AF Littke, GC Fu - Angewandte Chemie International Edition, 2002 - Wiley Online Library
Collectively, palladium‐catalyzed coupling reactions represent some of the most powerful
and versatile tools available to synthetic organic chemists. Their widespread popularity …

Palladium‐based catalytic systems for the synthesis of conjugated enynes by Sonogashira reactions and related alkynylations

H Doucet, JC Hierso - Angewandte Chemie International …, 2007 - Wiley Online Library
Conjugated alkynes are recurring building blocks in natural products, a wide range of
industrial intermediates, pharmaceuticals and agrochemicals, and molecular materials for …

Microwave-accelerated homogeneous catalysis in organic chemistry

M Larhed, C Moberg, A Hallberg - Accounts of chemical research, 2002 - ACS Publications
The efficiency of microwave flash heating in accelerating organic transformations (reaction
times reduced from days and hours to minutes and seconds) has recently been proven in …

Microwave enhanced synthesis

S Caddick, R Fitzmaurice - Tetrahedron, 2009 - Elsevier
Microwave technology has become very important in synthesis and it is reasonable to assert
that there are now very few areas of synthetic organic chemistry that have not been shown to …

Palladiumkatalysierte Kupplungen von Arylchloriden

AF Littke, GC Fu - Angewandte Chemie, 2002 - Wiley Online Library
Palladiumkatalysierte Kupplungen gehören zu den leistungsfähigsten und vielseitigsten
Reaktionen, die dem organischen Chemiker für die Synthese zur Verfügung stehen. Ihre …

Cross-Coupling and Dehalogenation Reactions Catalyzed by (N-Heterocyclic carbene)Pd(allyl)Cl Complexes

O Navarro, H Kaur, P Mahjoor… - The Journal of organic …, 2004 - ACS Publications
A series of well-defined, air-and moisture-stable (NHC) Pd (allyl) Cl (NHC= N-heterocyclic
carbene) complexes has been used in several catalytic reactions: Suzuki− Miyaura cross …

Kontrolliertes Erhitzen mit Mikrowellen in der modernen organischen Synthese

CO Kappe - Angewandte Chemie, 2004 - Wiley Online Library
Die offene Flamme konnte erst gezielt als Heizquelle für Reaktionsgefäße in der
Synthesechemie verwendet werden, nachdem Robert Bunsen 1855 den nach ihm …

Microwave‐enhanced enzyme reaction for protein mapping by mass spectrometry: A new approach to protein digestion in minutes

BN Pramanik, UA Mirza, YH Ing, YH Liu… - Protein …, 2002 - Wiley Online Library
Accelerated proteolytic cleavage of proteins under controlled microwave irradiation has
been achieved. Selective peptide fragmentation by endoproteases trypsin or lysine C led to …