The Chemical Reactivity of Membrane Lipids

G Duché, JM Sanderson - Chemical Reviews, 2024 - ACS Publications
It is well-known that aqueous dispersions of phospholipids spontaneously assemble into
bilayer structures. These structures have numerous applications across chemistry and …

Giant unilamellar vesicle electroformation: what to use, what to avoid, and how to quantify the results

Z Boban, I Mardešić, WK Subczynski, M Raguz - Membranes, 2021 - mdpi.com
Since its inception more than thirty years ago, electroformation has become the most
commonly used method for growing giant unilamellar vesicles (GUVs). Although the method …

Alveolar dynamics and beyond–the importance of surfactant protein C and cholesterol in lung homeostasis and fibrosis

K Sehlmeyer, J Ruwisch, N Roldan… - Frontiers in …, 2020 - frontiersin.org
Surfactant protein C (SP-C) is an important player in enhancing the interfacial adsorption of
lung surfactant lipid films to the alveolar air-liquid interface. Doing so, surface tension drops …

Failure of oxysterols such as lanosterol to restore lens clarity from cataracts

DM Daszynski, P Santhoshkumar, AS Phadte… - Scientific reports, 2019 - nature.com
The paradigm that cataracts are irreversible and that vision from cataracts can only be
restored through surgery has recently been challenged by reports that oxysterols such as …

Spatiotemporal changes in the human lens proteome: Critical insights into long-lived proteins

KL Schey, Z Wang, MG Friedrich, DL Garland… - Progress in retinal and …, 2020 - Elsevier
The ocular lens is a unique tissue that contains an age gradient of cells and proteins ranging
from newly differentiated cells containing newly synthesized proteins to cells and proteins …

Mechanical properties of the high cholesterol-containing membrane: An AFM study

NK Khadka, R Timsina, E Rowe, M O'Dell… - Biochimica et Biophysica …, 2021 - Elsevier
Cholesterol (Chol) content in most cellular membranes does not exceed 50 mol%, only in
the eye lens's fiber cell plasma membrane, its content surpasses 50 mol%. At this high …

Association of alpha-crystallin with fiber cell plasma membrane of the eye lens accompanied by light scattering and cataract formation

R Timsina, L Mainali - Membranes, 2021 - mdpi.com
α-crystallin is a major protein found in the mammalian eye lens that works as a molecular
chaperone by preventing the aggregation of proteins and providing tolerance to stress in the …

Optimization of Giant Unilamellar Vesicle Electroformation for Phosphatidylcholine/Sphingomyelin/Cholesterol Ternary Mixtures

Z Boban, I Mardešić, WK Subczynski, D Jozić, M Raguz - Membranes, 2022 - mdpi.com
Artificial vesicles are important tools in membrane research because they enable studying
membrane properties in controlled conditions. Giant unilamellar vesicles (GUVs) are …

Photoregulated “Breathing” Vesicle with Inversed Supramolecular Chirality

Q Cheng, H Duan, A Hao, P Xing - ACS Applied Materials & …, 2020 - ACS Publications
Though phospholipids possess chiral centers, their chiral aggregation within bilayer cell
membranes has seldom been referred and recognized. Insight into the chirality at higher …

Protective role of sphingomyelin in eye lens cell membrane model against oxidative stress

M Ravandeh, G Coliva, H Kahlert, A Azinfar, CA Helm… - Biomolecules, 2021 - mdpi.com
In the eye lens cell membrane, the lipid composition changes during the aging process: the
proportion of sphingomyelins (SM) increases, that of phosphatidylcholines decreases. To …