Aerobic organisms use molecular oxygen in several reactions, including those in which the
oxidation of substrate molecules is coupled to oxygen reduction to produce large amounts of …

In the 21st century, human aging will be one of the biggest challenges for most societies
throughout the world. The decline in human fitness is a typical hallmark of the aging process …

Oxidative stress has been implicated broadly as a cause of cell death and neural
degeneration in multiple disease conditions; however, the evidence for successful …

The main purpose of this study was to determine whether supplemental intake of coenzyme
Q10 (CoQ)(ubiquinone-10) or α-tocopherol, either alone or together, could improve brain …

Coenzyme Q10 (CoQ) is widely available as a dietary supplement and remains under
consideration as a treatment for age-associated neurodegenerative conditions. However, no …

The present study investigated the relationships among oxidative stress, β-amyloid and
cognitive abilities in the APP/PSEN1 double-transgenic mouse model of Alzheimer's …

The main purpose of this study was to investigate whether consumption of diets enriched in
antioxidants attenuates the level of oxidative stress in the senescence-accelerated mouse …

Limiting enzymes in the synthesis of brain monoamines seems to be susceptible to oxidative
damage, one of the most important factors in aging. It has been suggested that the use of …

We have tested the cognitive abilities of young (2.5 months) and middle-aged (14 months)
wild-type C57Bl/6J mice in the IntelliCage, which enables automated monitoring of …

Abstract Coenzyme Q 10 (CoQ 10) is widely consumed as a dietary supplement to enhance
bioenergetic capacity and to ameliorate the debilitative effects of the aging process or …