Phospholipid remodeling in physiology and disease

B Wang, P Tontonoz - Annual review of physiology, 2019 - annualreviews.org
Phospholipids are major constituents of biological membranes. The fatty acyl chain
composition of phospholipids determines the biophysical properties of membranes and …

Neuronal lipid metabolism: multiple pathways driving functional outcomes in health and disease

TJ Tracey, FJ Steyn, EJ Wolvetang… - Frontiers in molecular …, 2018 - frontiersin.org
Lipids are a fundamental class of organic molecules implicated in a wide range of biological
processes related to their structural diversity, and based on this can be broadly classified …

How protons pave the way to aggressive cancers

P Swietach, E Boedtkjer, SF Pedersen - Nature Reviews Cancer, 2023 - nature.com
Cancers undergo sequential changes to proton (H+) concentration and sensing that are
consequences of the disease and facilitate its further progression. The impact of protonation …

Artificial transmembrane ion transporters as potential therapeutics

J Yang, G Yu, JL Sessler, I Shin, PA Gale, F Huang - Chem, 2021 - cell.com
Various artificial transmembrane transporters, designed to function through mobile carrier or
channel mechanisms, have been developed in the past decade. With the aid of structural …

Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease

JFC Glatz, JJFP Luiken, A Bonen - Physiological reviews, 2010 - journals.physiology.org
Long-chain fatty acids and lipids serve a wide variety of functions in mammalian
homeostasis, particularly in the formation and dynamic properties of biological membranes …

[HTML][HTML] Taste of fat: a sixth taste modality?

P Besnard, P Passilly-Degrace… - Physiological …, 2015 - journals.physiology.org
An attraction for palatable foods rich in lipids is shared by rodents and humans. Over the last
decade, the mechanisms responsible for this specific eating behavior have been actively …

Carotenoids as membrane stabilizers in chloroplasts

M Havaux - Trends in plant science, 1998 - cell.com
In addition to their well-established function as collectors of light energy for photosynthesis
and as quenchers of triplet chlorophyll and singlet oxygen, carotenoids of higher plant …

[HTML][HTML] The ADP and ATP transport in mitochondria and its carrier

M Klingenberg - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2008 - Elsevier
Different from some more specialised short reviews, here a general although not
encyclopaedic survey of the function, metabolic role, structure and mechanism of the …

[HTML][HTML] Uncoupling: new approaches to an old problem of bioenergetics

VP Skulachev - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1998 - Elsevier
Some time ago, I wrote a review entitled ''Uncoupling of respiration and phosphorylation''for
the wx book ''Frontier of Cellular Bioenergetics''1. In that Ž. paper I hypothesized that i the …

[HTML][HTML] Brain docosahexaenoic acid uptake and metabolism

RJS Lacombe, R Chouinard-Watkins… - Molecular Aspects of …, 2018 - Elsevier
Docosahexaenoic acid (DHA) is the most abundant n-3 polyunsaturated fatty acid in the
brain where it serves to regulate several important processes and, in addition, serves as a …